How leisure activities affect health: a narrative review and multi-level theoretical framework of mechanisms of action
There is a large and growing body of evidence on the health benefits of engagement in
leisure activities (voluntary, enjoyable non-work activities, such as hobbies, arts …
leisure activities (voluntary, enjoyable non-work activities, such as hobbies, arts …
Targeting the molecular & cellular pillars of human aging with exercise
Biological aging is the main driver of age‐associated chronic diseases. In 2014, the United
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
[HTML][HTML] Stress, diet, exercise: Common environmental factors and their impact on epigenetic age
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …
health conditions in clinical and research settings. They have enabled geroscientists to …
Education and lifestyle factors are associated with DNA methylation clocks in older African Americans
DNA methylation (DNAm) clocks are important biomarkers of cellular aging and are
associated with a variety of age-related chronic diseases and all-cause mortality. Examining …
associated with a variety of age-related chronic diseases and all-cause mortality. Examining …
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
Exercise training prevents age‐related decline in muscle function. Targeting epigenetic
aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …
aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …
The older Finnish Twin Cohort—45 years of follow-up
J Kaprio, S Bollepalli, J Buchwald… - Twin Research and …, 2019 - cambridge.org
The older Finnish Twin Cohort (FTC) was established in 1974. The baseline survey was in
1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments …
1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments …
“Epigenetic clocks”: Theory and applications in human biology
CP Ryan - American Journal of Human Biology, 2021 - Wiley Online Library
All humans age, but how we age—and how fast—differs considerably from person to
person. This deviation between apparent age and chronological age is often referred to as …
person. This deviation between apparent age and chronological age is often referred to as …
Socioeconomic status, lifestyle, and DNA methylation age among racially and ethnically diverse adults: NIMHD Social Epigenomics Program
AK Maunakea, K Phankitnirundorn, R Peres… - JAMA Network …, 2024 - jamanetwork.com
Importance Variation in DNA methylation at specific loci estimates biological age, which is
associated with morbidity, mortality, and social experiences. Aging estimates known as …
associated with morbidity, mortality, and social experiences. Aging estimates known as …
[HTML][HTML] Leisure-time and occupational physical activity associates differently with epigenetic aging
Purpose Greater leisure-time physical activity (LTPA) associates with healthier lives, but
knowledge regarding occupational physical activity (OPA) is more inconsistent. DNA …
knowledge regarding occupational physical activity (OPA) is more inconsistent. DNA …
Associations between cardiorespiratory fitness and lifestyle‐related factors with DNA methylation‐based ageing clocks in older men: WASEDA'S Health Study
DNA methylation‐based age estimators (DNAm ageing clocks) are currently one of the most
promising biomarkers for predicting biological age. However, the relationships between …
promising biomarkers for predicting biological age. However, the relationships between …