The rapid detection of microbial agents is essential for the effective initiation of host defence
mechanisms against infection. Understanding how cells detect cytosolic DNA to trigger …

Objective To update the projected prevalence of arthritis and arthritis‐attributable activity
limitations among US adults, using a newer baseline for estimates. Methods Baseline …

Background: In the United States, doctor-diagnosed arthritis is a common and disabling
chronic condition. Arthritis can lead to severe joint pain and poor physical function, and it …

Macrophage-mediated inflammation is thought to have a causal role in osteoarthritis-related
pain and severity, and has been suggested to be triggered by endotoxins produced by the …

Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is
accumulating evidence to suggest that OA is an inflammatory disease of the entire synovial …

Objective To determine the relative incidence, prevalence, costs, and impact on disability of
8 common conditions treated by rehabilitation professionals. Data Sources Comprehensive …

Osteoarthritis is a debilitating disease that has increased in prevalence across the world due
to the aging population. Currently, physicians use a plethora of treatment strategies to try …

Chronic pain broadly encompasses both objectively defined conditions and idiopathic
conditions that lack physical findings. Despite variance in origin or pathogenesis, these …

Osteoarthritis is a complex, multifactorial disease, and there is still much to learn regarding
mechanisms underlying incidence and progression. However, there are several known …

Robotic-assisted orthopedic surgery has been available clinically in some form for over 2
decades, claiming to improve total joint arthroplasty by enhancing the surgeon's ability to …