ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

M Hoogman, D Van Rooij, M Klein… - Human brain …, 2022 - Wiley Online Library
Neuroimaging has been extensively used to study brain structure and function in individuals
with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over …

[HTML][HTML] Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA

J Radua, E Vieta, R Shinohara, P Kochunov, Y Quidé… - Neuroimage, 2020 - Elsevier
A common limitation of neuroimaging studies is their small sample sizes. To overcome this
hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) …

[HTML][HTML] Brain correlates of depression, post-traumatic distress, and inflammatory biomarkers in COVID-19 survivors: A multimodal magnetic resonance imaging study

F Benedetti, M Palladini, M Paolini, E Melloni… - Brain, behavior, & …, 2021 - Elsevier
Psychiatric sequelae substantially contribute to the post-acute burden of disease associated
with COVID-19, persisting months after clearance of the virus. Brain imaging shows white …

Astrocyte regulation of synaptic signaling in psychiatric disorders

A Kruyer, PW Kalivas, MD Scofield - Neuropsychopharmacology, 2023 - nature.com
Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

A unified model of the pathophysiology of bipolar disorder

P Magioncalda, M Martino - Molecular Psychiatry, 2022 - nature.com
This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …

Association between diffusion tensor imaging, inflammation and immunological alterations in unipolar and bipolar depression: a review

R Aronica, P Enrico, L Squarcina, P Brambilla… - Neuroscience & …, 2022 - Elsevier
Abstract Major Depressive Disorder (MDD) and Bipolar Disorder Depression (BDD) are
common psychiatric illnesses characterized by structural and functional brain alterations and …

Trends in big data analyses by multicenter collaborative translational research in psychiatry

T Onitsuka, Y Hirano, K Nemoto… - Psychiatry and …, 2022 - Wiley Online Library
The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …

[HTML][HTML] Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

G Scaini, SS Valvassori, AP Diaz, CN Lima… - Brazilian Journal of …, 2020 - SciELO Brasil
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Diagnosis and management of bipolar disorders

FS Goes - bmj, 2023 - bmj.com
Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …