Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

IgE, the key molecule in atopy has been shown to bind two receptors, FcεRI, the high‐affinity
receptor, and FcεRII (CD23), binding IgE with lower affinity. Whereas cross‐linking of IgE on …

Background The involvement of B cells in allergen tolerance induction remains largely
unexplored. This study investigates the role of B cells in this process, by comparing B‐cell …

Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated
hypersensensitivity disease. It is based on the production of IgE antibodies and T cell …

Immunoglobulin E (IgE) is the key immunoglobulin in the pathogenesis of IgE associated
allergic diseases affecting 30% of the world population. Recent data suggest that allergen …

Background Type I hypersensitivity is mediated by allergen-specific IgE, which sensitizes the
high-affinity IgE receptor FcεRI on mast cells and basophils and drives allergic inflammation …

It is well established that immunoglobulin E (IgE) plays a crucial role in atopy by binding to
two types of Fcε receptors (FcεRI and FcεRII, also known as CD23). The cross-linking of …

Fish allergy is one of the “big nine” categories of food allergens worldwide, and its
prevalence is increasing with the higher demand for this nutritious food source. Fish …

Background The low-affinity receptor for IgE, FcεRII (CD23), contributes to allergic
inflammation through allergen presentation to T cells, regulation of IgE responses, and …

IgM is the first antibody to be produced in immune responses and plays an important role in
the neutralization of bacteria and viruses. Human IgM is heavily glycosylated, featuring five …