Vascular nitric oxide resistance in type 2 diabetes

Z Bahadoran, P Mirmiran, K Kashfi, A Ghasemi - Cell Death & Disease, 2023 - nature.com
Vascular nitric oxide (NO•) resistance, manifested by an impaired vasodilator function of NO•
in both the macro-and microvessels, is a common state in type 2 diabetes (T2D) associated …

Recent advances in the combination of organic solvent-free extraction, chemical standardization, antioxidant assay, and cell culture metabolomics for functional food …

CH Leo, ES Ong - Critical Reviews in Food Science and Nutrition, 2024 - Taylor & Francis
Functional foods and their by-products contain a wide range of bioactive components with
an array of health benefits and were proposed to improve public health, well-being, and …

Dieckol isolated from brown seaweed Ecklonia cava attenuates type ІІ diabetes in db/db mouse model

MC Kang, W Wijesinghe, SH Lee, SM Kang… - Food and chemical …, 2013 - Elsevier
In the present study, the attenuation of type ІІ diabetes by dieckol, a phlorotannin derivative
isolated from brown seaweed, Ecklonia cava was investigated in C57BL/KsJ-db/db, a type ІІ …

Mulberry (Morus alba L.) Fruit Extract Containing Anthocyanins Improves Glycemic Control and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in …

KH Choi, HA Lee, MH Park, JS Han - Journal of Medicinal Food, 2016 - liebertpub.com
The effect of mulberry (Morus alba L.) fruit extract (MFE) on hyperglycemia and insulin
sensitivity in an animal model of type 2 diabetes was evaluated. C57BL/Ksj-diabetic db/db …

Valorization of avocado seeds with antioxidant capacity using pressurized hot water extraction

ES Ong, J Low, JCW Tan, SY Foo, CH Leo - Scientific Reports, 2022 - nature.com
The pulp of avocado (Persea Americana) is widely consumed as the primary food source,
while the seed is often discarded as food waste. Increased consumption of avocado would …

Green extraction of orange peel waste reduces TNFα-induced vascular inflammation and endothelial dysfunction

CH Leo, SY Foo, JCW Tan, UX Tan, CK Chua, ES Ong - Antioxidants, 2022 - mdpi.com
Orange peel waste (OPW) is known to contain an abundant amount of polyphenols
compounds such as flavonoids, well-reported for their antioxidant and anti-inflammatory …

Pressurized hot water extraction of okra seeds reveals antioxidant, antidiabetic and vasoprotective activities

ES Ong, CLY Oh, JCW Tan, SY Foo, CH Leo - Plants, 2021 - mdpi.com
Abelmoschus esculentus L. Moench (okra) is a commonly consumed vegetable that consists
of the seeds and peel component which are rich in polyphenolic compounds. The aim of this …

Antioxidant and Cytoprotective Effect of Quinoa (Chenopodium quinoa Willd.) with Pressurized Hot Water Extraction (PHWE)

ES Ong, CJN Pek, JCW Tan, CH Leo - Antioxidants, 2020 - mdpi.com
Quinoa is widely noted for its nutritional value. The seed is the main edible part of the plant
and exists in at least three different colors: white, red and black. This study utilized a …

3D printed nutritious snacks from orange peel waste

CH Leo, CP Lee, SY Foo, JCW Tan, J Da Tan… - Materials Today …, 2022 - Elsevier
The discarded section of an orange fruit, orange peel waste (OPW), is well-recognised as a
rich source of vitamins and nutrients that can be turned into high-value-added food products …

Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats

K Serizawa, K Yogo, K Aizawa, Y Tashiro… - Cardiovascular …, 2011 - Springer
Background Nicorandil, an anti-angina agent, reportedly improves outcomes even in angina
patients with diabetes. However, the precise mechanism underlying the beneficial effect of …