Delivery systems for mitochondrial gene therapy: a review
R Faria, P Boisguérin, Â Sousa, D Costa - Pharmaceutics, 2023 - mdpi.com
Mitochondria are membrane-bound cellular organelles of high relevance responsible for the
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …
[HTML][HTML] Mitochondrial DNA-targeted therapy: A novel approach to combat cancer
Y Lin, B Yang, Y Huang, Y Zhang, Y Jiang, L Ma… - Cell Insight, 2023 - Elsevier
Mitochondrial DNA (mtDNA) encodes proteins and RNAs that are essential for mitochondrial
function and cellular homeostasis, and participates in important processes of cellular …
function and cellular homeostasis, and participates in important processes of cellular …
A switch in N-terminal capping of β-peptides creates novel self-assembled nanoparticles
Small tripeptides composed entirely of β3-amino acids have been shown to self-assemble
into fibres following acylation of the N-terminus. Given the use of Fmoc as a strategy to …
into fibres following acylation of the N-terminus. Given the use of Fmoc as a strategy to …
Emerging landscape of cell-penetrating peptide-mediated organelle restoration and replacement
Organelles are specialized subunits within a cell membrane that perform specific roles or
functions, and their dysfunction can lead to a variety of pathophysiologies including …
functions, and their dysfunction can lead to a variety of pathophysiologies including …
Evidence That a Peptide-Drug/p53 Gene Complex Promotes Cognate Gene Expression and Inhibits the Viability of Glioblastoma Cells
Glioblastoma multiform (GBM) is considered the deadliest brain cancer. Conventional
therapies are followed by poor patient survival outcomes, so novel and more efficacious …
therapies are followed by poor patient survival outcomes, so novel and more efficacious …
[HTML][HTML] Upgrading Mitochondria-Targeting Peptide-Based Nanocomplexes for Zebrafish In Vivo Compatibility Assays
R Faria, E Vivès, P Boisguérin, S Descamps, Â Sousa… - Pharmaceutics, 2024 - mdpi.com
The lack of effective delivery systems has slowed the development of mitochondrial gene
therapy. Delivery systems based on cell-penetrating peptides (CPPs) like the WRAP …
therapy. Delivery systems based on cell-penetrating peptides (CPPs) like the WRAP …
Optimization of Dendritic Polypeptide Delivery System for Antisense Antibacterial Agents Targeting ftsZ
Y Li, Y Hu, Z Kamal, Y Chen, X Xue, S Yao, H Zhao… - ACS …, 2024 - ACS Publications
There is an urgent requirement for a novel treatment strategy for drug-resistant
Staphylococcus aureus (S. aureus) infection. Antisense antimicrobials are promising …
Staphylococcus aureus (S. aureus) infection. Antisense antimicrobials are promising …
«New Modalities in Cancer Imaging and Therapy» XVe édition de l'atelier organisé par le réseau «Vectorisation, Imagerie, Radiothérapies» du Cancéropôle Grand …
F Léost, J Barbet, M Beyler, M Chérel, G Delpon… - Bulletin du …, 2023 - Elsevier
Résumé La quinzième édition de l'atelier international organisé par le réseau
«Vectorisation, Imagerie, Radiothérapies» du Cancéropôle Grand-Ouest a porté sur les …
«Vectorisation, Imagerie, Radiothérapies» du Cancéropôle Grand-Ouest a porté sur les …
Targeting Specific Barriers
Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
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Account Menu Find a journal Publish with us Track your research Search Cart Book cover …
Account Menu Find a journal Publish with us Track your research Search Cart Book cover …
[PDF][PDF] Desenvolvimento de vetores baseados em péptidos para direcionamento à mitocôndria
SCMD Varela - 2023 - core.ac.uk
As mitocôndrias são organelos citoplasmáticos presentes na maioria das células
eucarióticas sendo responsáveis pela produção de 90% de ATP, moléculas indispensáveis …
eucarióticas sendo responsáveis pela produção de 90% de ATP, moléculas indispensáveis …