MicroRNAs as diagnostic and prognostic biomarkers in ischemic stroke—a comprehensive review and bioinformatic analysis

C Eyileten, Z Wicik, S De Rosa, D Mirowska-Guzel… - Cells, 2018 - mdpi.com
Stroke is the second-most common cause of death worldwide. The pathophysiology of
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …

Microfluidic‐integrated biosensors: Prospects for point‐of‐care diagnostics

S Kumar, S Kumar, MA Ali, P Anand… - Biotechnology …, 2013 - Wiley Online Library
There is a growing demand to integrate biosensors with microfluidics to provide miniaturized
platforms with many favorable properties, such as reduced sample volume, decreased …

An amplification-free electrochemical detection of exosomal miRNA-21 in serum samples

K Boriachek, M Umer, MN Islam, V Gopalan, AK Lam… - Analyst, 2018 - pubs.rsc.org
Recent evidence suggests that small non-coding RNAs such as microRNA (miRNA)
encapsulated in exosomes represent an important mechanism of communication between …

Colorimetric detection of small molecules in complex matrixes via target-mediated growth of aptamer-functionalized gold nanoparticles

JH Soh, Y Lin, S Rana, JY Ying… - Analytical …, 2015 - ACS Publications
A versatile and sensitive colorimetric assay that allows the rapid detection of small-molecule
targets using the naked eye is demonstrated. The working principle of the assay integrates …

Native MicroRNA targets trigger self‐assembly of nanozyme‐patterned hollowed nanocuboids with optimal interparticle gaps for plasmonic‐activated cancer detection

J Li, KM Koo, Y Wang, M Trau - Small, 2019 - Wiley Online Library
The modernized use of nucleic acid (NA) sequences to drive nanostructure self‐assembly
has given rise to a new class of designed nanomaterials with controllable plasmonic …

Emerging isothermal amplification technologies for microRNA biosensing: Applications to liquid biopsies

G Gines, R Menezes, W Xiao, Y Rondelez… - Molecular Aspects of …, 2020 - Elsevier
The potential of microRNAs (miRNAs) as biomarker candidates in clinical practice for
diagnosis, prognosis and treatment response prediction, especially in liquid biopsies, has …

An electrochemical ELISA-like immunosensor for miRNAs detection based on screen-printed gold electrodes modified with reduced graphene oxide and carbon …

HV Tran, B Piro, S Reisberg, LH Nguyen… - Biosensors and …, 2014 - Elsevier
We design an electrochemical immunosensor for miRNA detection, based on screen-printed
gold electrodes modified with reduced graphene oxide and carbon nanotubes. An original …

miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine?

E Goretti, DR Wagner, Y Devaux - Trends in molecular medicine, 2014 - cell.com
miRNAs are small noncoding RNAs known to post-transcriptionally regulate gene
expression. miRNAs are expressed in the heart where they regulate multiple …

Ultrasensitive electroanalysis of low-level free microRNAs in blood by maximum signal amplification of catalytic silver deposition using alkaline phosphatase …

Y Si, Z Sun, N Zhang, W Qi, S Li, L Chen… - Analytical …, 2014 - ACS Publications
An ultrasensitive sandwich-type analysis method has been initially developed for probing
low-level free microRNAs (miRNAs) in blood by a maximal signal amplification protocol of …

Colorimetric Detection of Hg2+ Based on the Growth of Aptamer‐Coated AuNPs: The Effect of Prolonging Aptamer Strands

L Tan, Z Chen, C Zhang, X Wei, T Lou, Y Zhao - Small, 2017 - Wiley Online Library
Herein, a versatile and sensitive colorimetric sensor for Hg2+ based on aptamer–target
specific binding and target‐mediated growth of AuNPs is reported. The 15 T bases are first …