Curcumin-based nanoformulations: A promising adjuvant towards cancer treatment

S Hafez Ghoran, A Calcaterra, M Abbasi, F Taktaz… - Molecules, 2022 - mdpi.com
Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

Non-destructive monitoring of 3D cell cultures: new technologies and applications

M Cortesi, E Giordano - PeerJ, 2022 - peerj.com
Abstract 3D cell cultures are becoming the new standard for cell-based in vitro research, due
to their higher transferrability toward in vivo biology. The lack of established techniques for …

Melatonin and endothelial cell-loaded alginate-fibrin hydrogel promoted angiogenesis in rat cryopreserved/thawed ovaries transplanted to the heterotopic sites

M Izadpanah, AR Del Bakhshayesh, Z Bahroudi… - Journal of Biological …, 2023 - Springer
Background Ischemic niche can promote follicular atresia following the transplantation of
cryopreserved/thawed ovaries to the heterotopic sites. Thus, the promotion of blood supply …

Investigation of antifouling and antibacterial properties of curcumin-enriched surfactant nanoparticles modified polysulfone nanocomposite membranes

S Chaubey, S Mehra, A Yadav, A Kumar… - Materials Today …, 2022 - Elsevier
Membrane fouling is the major hindrance to the extensive application of membrane-based
treatment techniques. In this study, we synthesized the antibacterial membranes with varying …

Melatonin blunted the angiogenic activity in 3D colon cancer tumoroids by the reduction of endocan

MT Narmi, HM Shoja, S Haiaty, M Mahdipour… - Cancer Cell …, 2023 - Springer
Background Complexity and heterogeneity of the tumor niche are closely associated with
the failure of therapeutic protocols. Unfortunately, most data have been obtained from …

Anti-cancer effects of artesunate in human 3D tumor models of different complexity

M Niederreiter, J Klein, K Arndt, J Werner… - International Journal of …, 2023 - mdpi.com
The anti-malaria drug Artesunate (ART) shows strong anti-cancer effects in vitro; however, it
shows only marginal treatment results in clinical cancer studies. In this study, ART was …

Anti-proliferative and apoptotic effect of gemini curcumin in p53-wild type and p53-mutant colorectal cancer cell lines

M Ebrahimi, E Babaei, F Neri, MAH Feizi - International Journal of …, 2021 - Elsevier
Background Despite recent advances in therapy, colorectal cancer remains a leading cause
of death in affected people. Curcumin is the main bioactive compound of turmeric that has …

Photothermal effect of albumin-modified gold nanorods diminished neuroblastoma cancer stem cells dynamic growth by modulating autophagy

ZA Shahabad, CB Avci, F Bani, A Zarebkohan… - Scientific Reports, 2022 - nature.com
Here, we investigated the photothermal effect of gold nanorods (GNRs) on human
neuroblastoma CD133+ cancer stem cells (CSCs) via autophagic cell death. GNRs were …

Nanoformulation of polyphenol curcumin enhances cisplatin-induced apoptosis in drug-resistant MDA-MB-231 breast cancer cells

P Karami, G Othman, Z Housein, A Salihi… - Molecules, 2022 - mdpi.com
Triple Negative Breast Cancer (TNBC) is the aggressive and lethal type of breast
malignancy that develops resistance to current therapies. Combination therapy has proven …

Hyper-branched cationic cyclodextrin polymers for improving plasmid transfection in 2D and 3D spheroid cells

YK Monfared, M Mahmoudian, C Cecone, F Caldera… - Pharmaceutics, 2022 - mdpi.com
In this article, we used monolayer two dimensional (2D) and 3D multicellular spheroid
models to improve our understanding of the gene delivery process of a new modified …