[HTML][HTML] Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): an expert opinion meeting report

RJ Andrade, GP Aithal, YS De Boer, R Liberal… - Journal of …, 2023 - Elsevier
Drug-induced liver injury (DILI) can mimic almost all other liver disorders. A phenotype
increasingly ascribed to drugs is autoimmune-like hepatitis (ALH). This article summarises …

[HTML][HTML] Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD

E Smirnova, MD Muthiah, N Narayan, MS Siddiqui… - Hepatology, 2022 - journals.lww.com
Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

[PDF][PDF] Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis

C Harrington, S Krishnan, CL Mack, P Cravedi… - …, 2022 - Wiley Online Library
Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

[HTML][HTML] Idiosyncratic drug-induced liver injury: mechanistic and clinical challenges

A Jee, SC Sernoskie, J Uetrecht - International journal of molecular …, 2021 - mdpi.com
Idiosyncratic drug-induced liver injury (IDILI) remains a significant problem for patients and
drug development. The idiosyncratic nature of IDILI makes mechanistic studies difficult, and …

Anticardiolipin and other antiphospholipid antibodies in critically ill COVID-19 positive and negative patients

U Trahtemberg, R Rottapel, CC Dos Santos… - Annals of the …, 2021 - ard.bmj.com
Background Reports of severe COVID-19 being associated with thrombosis,
antiphospholipid antibodies (APLA), and antiphospholipid syndrome have yielded disparate …

[PDF][PDF] Setting up criteria for drug‐induced autoimmune‐like hepatitis through a systematic analysis of published reports

ES Björnsson, I Medina‐Caliz… - Hepatology …, 2022 - Wiley Online Library
Nitrofurantoin, minocycline, methyldopa and infliximab, have been found to induce
autoimmune‐like hepatitis (DI‐AILH). Evidence for other drugs and herbal and dietary …

Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries

M García‐Cortés, A Ortega‐Alonso… - Liver …, 2023 - Wiley Online Library
Background & aims Idiosyncratic drug‐induced liver injury (DILI) with autoimmune features
is a liver condition with laboratory and histological characteristics similar to those of …

[HTML][HTML] Autoantibodies present in hidradenitis suppurativa correlate with disease severity and promote the release of proinflammatory cytokines in macrophages

C Carmona-Rivera, LJ O'Neil, E Patino-Martinez… - Journal of Investigative …, 2022 - Elsevier
Hidradenitis suppurativa (HS), also known as acne inversa, is a debilitating inflammatory
skin disorder that is characterized by nodules that lead to the development of connected …

[HTML][HTML] B cells in autoimmune hepatitis: bystanders or central players?

C Schultheiß, S Steinmann, AW Lohse… - Seminars in …, 2022 - Springer
B cells are central for the adaptive immune system to mount successful immune responses
not only as antibody producers but also as regulators of cellular immunity. These …

[PDF][PDF] Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis

R Taubert, B Engel, J Diestelhorst… - …, 2022 - Wiley Online Library
Abstract Background and Aims Detection of autoantibodies is a mainstay of diagnosing
autoimmune hepatitis (AIH). However, conventional autoantibodies for the workup of AIH …