Suppression of COX-2/PGE2 levels by carbazole-linked triazoles via modulating methylglyoxal-AGEs and glucose-AGEs–induced ROS/NF-κB signaling in monocytes
Chronic hyperglycemia favours the formation of advanced glycation end products (AGEs)
which are responsible of many diabetic vascular complications. Keeping in view the …
which are responsible of many diabetic vascular complications. Keeping in view the …
[HTML][HTML] Exploring bi-carbazole-linked triazoles as inhibitors of prolyl endo peptidase via integrated in vitro and in silico study
S Ullah, F Mansoor, SA Khan, U Jabeen, AI Almars… - Scientific Reports, 2024 - nature.com
A serine protease called prolyl endopeptidase (PEP) hydrolyses the peptide bonds on the
carboxy side of the proline ring. The excessive PEP expression in brain results in …
carboxy side of the proline ring. The excessive PEP expression in brain results in …
Heterosiklik 4, 5-dihidro-1H-1, 2, 4-triazol-5-on türevinin antioksidan özelliğinin erkek ratlarda (wistar albino) in vivo olarak belirlenmesi
4, 5-Dihidro-1H-1, 2, 4-triazol-5-on türevli heterosiklik bileşikler sanayide, tıpta, eczacılıkta
ve kimyanın pek çok alanında önemli yere sahiptir. Bu bileşiklerin bazı biyolojik aktivite …
ve kimyanın pek çok alanında önemli yere sahiptir. Bu bileşiklerin bazı biyolojik aktivite …
Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4, 5, 6, 7-tetrahydrobenzo [b] thiophen-2-yl) naphthalene-1-sulfonamide …
Liver pyruvate kinase (PKL) is a key player in controlling metabolic pathways and ATP
production within the liver's glycolysis pathway. Since PKL modulators have been identified …
production within the liver's glycolysis pathway. Since PKL modulators have been identified …
Preparation and study of poly (9-methylcarbazole) and poly (9-ethylcarbazole) films by electrochemical oxidation of monomers and dimers
In the present study, we succeed in depositing poly (9-methylcarbazole) and poly (9-
ethylcarbazole) films by electrochemical oxidation using dichloromethane as solvent. Poly (9 …
ethylcarbazole) films by electrochemical oxidation using dichloromethane as solvent. Poly (9 …
Synthesis, crystal structure, and reactive oxygen species (ROS) inhibition of N–and O–linked triazole analogues of harmine
Reactive oxygen species (ROS) have been reported in the literature for their important role
in the progression of oxidative stress which results in several pathological conditions …
in the progression of oxidative stress which results in several pathological conditions …
Construction of 3, 3'‐Bicarbazoles and Indolocarbazoles by Using Visible Light
A synthetic and mechanistic study of novel iterative double cyclization intramolecular SRN1
reactions from diarylamines bearing two aryl halide moieties was carried out. This …
reactions from diarylamines bearing two aryl halide moieties was carried out. This …
[PDF][PDF] Exploring the diastereoselectivity for Fischer indolization of L-menthone under different conditions, spectral characterization, and biological activities of new (2R …
S Rasheed, R Sadiq, FZ Basha - European Journal of Chemistry, 2022 - academia.edu
Tetrahydrocarbazole is defined as an indole skeleton fused with a cyclohexane ring. This
class is widely distributed in nature and has gained immense attention of medicinal chemists …
class is widely distributed in nature and has gained immense attention of medicinal chemists …