Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

Bacterial biofilm‐associated infections (BAIs) are the leading cause of prosthetic implant
failure. The dense biofilm structure prevents antibiotic penetration, while the highly acidic …

Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

Diabetic wound is one of the most intractable chronic wounds that is prone to bacterial
infection. Hypoxia is an important feature in its microenvironment. However, it is challenging …

Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …