Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin
gene that leads to the production of abnormal hemoglobin called hemoglobin S. The …

Blood is the most intensely studied human biofluid and is used as the main indicator of the
health status of an individual. Blood is a very complex fluid, containing a multiplicity of …

Sickle cell disease affects 25% of people living in Central and West Africa and, if left
undiagnosed, can cause life threatening “silent” strokes and lifelong damage. However …

ABSTRACT Introduction: Sickle Cell Disease (SCD) affects 100,000 Americans and more
than 14 million people globally, mostly in economically disadvantaged populations, and …

Sickle cell disease (SCD) is a common and life‐threatening hematological disorder,
affecting approximately 400,000 newborns annually worldwide. Most SCD births occur in …

Sickle cell disease (SCD) is a serious and life-threatening disorder. SCD is considered a
public health issue affecting 25% of the population in Central and West Africa. Some …

Background The high childhood mortality and life-long complications associated with sickle
cell anemia (SCA) in developing countries could be significantly reduced with effective …

FUNDING: This work was supported by the National Heart, Lung, and Blood Institute Award
K23-HL128885-01. The content is solely the responsibility of the authors and does not …

The high cost, complexity and reliance on electricity, specialized equipment and supplies
associated with conventional diagnostic methods limit the scope and sustainability of …

Red blood cells (RBCs), the most abundant cellular component in whole blood, are an
important health indicator, and the morphology and behavior of RBCs on porous paper …