Animal models for examining human breast cancer (HBC) carcinogenesis have been
extensively studied and proposed. With the recent advent of immunotherapy, significant …

Canine mammary tumours (CMTs) are the most common neoplasms in intact female dogs.
Although the prevalence of these tumours decreases in regions where preventive ovari …

In this prospective study, a canine-adapted histological grading method was compared with
histopathological and clinical characteristics and was evaluated as a prognostic indicator in …

The purpose of this paper is to establish criteria that could guide the diagnosis, prognosis
and treatment of canine mammary neoplasias. It was elaborated during the Mammary …

Despite recent major clinical breakthroughs in human cancer immunotherapy including the
use of checkpoint inhibitors and engineered T cells, important challenges remain, including …

Apoptosis is an important process involved in pathogenesis and progression of neoplasia.
However, it has been not so far extensively investigated in canine mammary tumors (CMTs) …

Purpose Relevant animal models of human breast cancer are currently needed, especially
for the aggressive triple-negative breast cancer subtype. Recent studies and our results …

Melatonin is a ubiquitous indole amine that plays a fundamental role in the regulation of the
biological rhythm. Disrupted circadian rhythm alters the expression of clock genes and …

Advances in biotechnology have enabled the collection of an immeasurable amount of
information from genomic, transcriptomic, metabolomic and proteomic studies of tumours …

Mixed tumors are the most frequent mammary gland neoplasms in bitches; however, studies
that thoroughly describe their clinicopathological data, treatment approaches, and the …