C-type lectin receptors (CLRs) are important pattern recognition receptors involved in
recognition and induction of adaptive immunity to pathogens. Certain CLRs play an …

The complement system is a key component of innate immunity which readily responds to
invading microorganisms. Activation of the complement system typically occurs via three …

CR3 and CR4 belong to the family of β 2-integrins and play an important role in
phagocytosis, cellular adherence and migration. CR3 and CR4 are generally expected to …

Scavenger receptors were originally defined by their ability to bind and internalize modified
lipoproteins. Macrophages express at least six structurally different cell surface receptors for …

Complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) belong to the family of
beta2 integrins and are expressed mainly by myeloid cell types in humans. Previously, we …

The involvement of complement in the regulation of antibody responses has been known for
long. By now several additional B cell functions–including cytokine production and antigen …

Components of the complement system and atypical parameters of coagulation were
reported in COVID-19 patients, as well as the exacerbation of the inflammation and …

Integrins are cell membrane receptors that are involved in essential physiological and
serious pathological processes. Their main role is to ensure a closely regulated link …

Highlights•Injection/infusion of nanopharmaceuticals may induce idiosyncratic adverse
reactions.•These reactions typically occur within minutes of the start of infusion.•The role of …

Humans respond differently than other primates to a large number of infections. Differences
in susceptibility to infectious agents between humans and other primates are probably due …