Molecular and genetic mechanisms of spinal stenosis formation: systematic review

VA Byvaltsev, AA Kalinin, PA Hernandez… - International Journal of …, 2022 - mdpi.com
Spinal stenosis (SS) is a multifactorial polyetiological condition characterized by the
narrowing of the spinal canal. This condition is a common source of pain among people over …

Anterior cervical controllable Antedisplacement and Fusion (ACAF) versus Anterior Cervical Corpectomy and Fusion (ACCF) for ossification of the cervical posterior …

M Wang, G Yang, B Zhou, Z Cao, Y Li, J Tan… - Neurosurgical …, 2024 - Springer
This study aimed to systematically review and compare the efficacy and safety of anterior
cervical controllable antedisplacement and fusion (ACAF) versus anterior cervical …

Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1

C Xu, Z Zhang, N Liu, L Li, H Zhong, R Wang… - Nature …, 2022 - nature.com
Ossification of the posterior longitudinal ligament (OPLL) is an emerging spinal disease
caused by heterotopic ossification of the posterior longitudinal ligament. The pathological …

[HTML][HTML] Genetic odyssey to ossification of the posterior longitudinal ligament in the cervical spine: a systematic review

YI Won, CH Lee, WT Yuh, SW Kwon, CH Kim… - Neurospine, 2022 - ncbi.nlm.nih.gov
Despite numerous studies, the pathogenesis of ossification of the posterior longitudinal
ligament (OPLL) is still unclear. Previous genetic studies proposed variations in genes …

Risk factors for surgical complications in the management of ossification of the posterior longitudinal ligament

MRD Ramos, G Liu, JH Tan, JHJ Tan, JNM Ruiz… - The Spine Journal, 2021 - Elsevier
ABSTRACT BACKGROUND CONTEXT Ossification of the posterior longitudinal ligament
(OPLL) is a progressive, debilitating disease most commonly affecting the cervical spine …

Comparison of Anterior Controllable Antedisplacement and Fusion Versus Laminoplasty in the treatment of Multisegment ossification of cervical posterior longitudinal …

Y Zhang, Z Huang, P Xu, Z Xu, X Xing, Y Xin, M Gao… - World Neurosurgery, 2024 - Elsevier
Objective This study aims to provide a comprehensive summary of the existing literature and
conduct a systematic evaluation of the clinical outcomes associated with anterior …

Comparison of anterior cervical discectomy and fusion versus anterior cervical corpectomy and fusion in the treatment of localized ossification of the posterior …

T Chen, Y Wang, H Zhou, C Lin, X Li… - Journal of …, 2023 - journals.sagepub.com
Background The retrospective study was conducted to compare the efficacy of anterior
cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) …

What is the impact of surgical approach in the treatment of degenerative cervical myelopathy in patients with OPLL? A propensity-score matched, multi-center analysis …

NJ Lee, V Boddapati, J Mathew, M Fields… - Global Spine …, 2023 - journals.sagepub.com
Study Design: Retrospective cohort. Objective: Provide a comparison of surgical approach in
the treatment of degenerative cervical myelopathy in patients with OPLL. Methods: A …

CTSD upregulation as a key driver of spinal ligament abnormalities in spinal stenosis

L Li, Z Zheng, J Jiang, J Chen, B Jiang, Y Li, Y Dai… - Bone, 2024 - Elsevier
Spinal stenosis (SS) is frequently caused by spinal ligament abnormalities, such as
ossification and hypertrophy, which narrow the spinal canal and compress the spinal cord or …

Treatment of thoracic ossification of posterior longitudinal ligament with one-stage 360 degree circumferential decompression assisted by piezosurgery

P Yang, R Ge, Z Chen, B Wen - Journal of Investigative Surgery, 2022 - Taylor & Francis
Objectives To evaluate the safety and clinical efficacy of One-Stage 360 degree circular
decompression for thoracic ossification of the posterior longitudinal ligament (TOPLL) …