Deciphering miRNAs' action through miRNA editing

M Correia de Sousa, M Gjorgjieva, D Dolicka… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene
expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) …

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …

Healthcare cost and utilization in nonalcoholic fatty liver disease: real‐world data from a large US claims database

AM Allen, HK Van Houten, LR Sangaralingham… - Hepatology, 2018 - journals.lww.com
Cystic fibrosis (CF)‐associated liver disease (CFLD) is a hepatobiliary complication of CF.
Current diagnostic modalities rely on nonspecific assessments, whereas liver biopsy is the …

Isomirs–hidden soldiers in the mirna regulatory army, and how to find them?

I Glogovitis, G Yahubyan, T Würdinger… - Biomolecules, 2020 - mdpi.com
Numerous studies on microRNAs (miRNA) in cancer and other diseases have been
accompanied by diverse computational approaches and experimental methods to predict …

FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis

R De Santis, L Santini, A Colantoni, G Peruzzi… - Stem cell reports, 2017 - cell.com
The FUS gene has been linked to amyotrophic lateral sclerosis (ALS). FUS is a ubiquitous
RNA-binding protein, and the mechanisms leading to selective motoneuron loss …

miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale

T Fehlmann, F Kern, O Laham, C Backes… - Nucleic acids …, 2021 - academic.oup.com
Analyzing all features of small non-coding RNA sequencing data can be demanding and
challenging. To facilitate this process, we developed miRMaster. After the analysis of over …

From follicle to blastocyst: microRNA-34c from follicular fluid-derived extracellular vesicles modulates blastocyst quality

C Benedetti, KC Pavani, Y Gansemans… - Journal of animal …, 2024 - Springer
Background Within the follicular fluid, extracellular vesicles (EVs) guide oocyte growth
through their cargo microRNAs (miRNAs). Here, we investigated the role of EVs and their …

Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence

X Lin, E Beckers, S Mc Cafferty, Y Gansemans… - Frontiers in …, 2019 - frontiersin.org
Recently, secreted microRNAs (miRNAs) have received a lot of attention since they may act
as autocrine factors. However, how secreted miRNAs influence embryonic development is …

Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing

Q Liu, C Ding, X Lang, G Guo, J Chen… - Briefings in …, 2021 - academic.oup.com
Abstract Small noncoding RNAs (sRNA/sncRNAs) are generated from different genomic loci
and play important roles in biological processes, such as cell proliferation and the regulation …

Altered microRNA expression profiles in large offspring syndrome and Beckwith-Wiedemann syndrome

Y Li, DE Hagen, T Ji, MR Bakhtiarizadeh… - Epigenetics, 2019 - Taylor & Francis
The use of assisted reproductive technologies (ART) can induce a congenital overgrowth
condition in humans and ruminants, namely Beckwith-Wiedemann syndrome (BWS) and …