Global trends in HIV infection demonstrate an overall increase in HIV prevalence and
substantial declines in AIDS related deaths largely attributable to the survival benefits of …

Objectives The objective of the study is to present the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) conceptual approach to the …

Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

Importance Human immunodeficiency virus (HIV) transmission risk is primarily dependent
on behavior (sexual and injection drug use) and HIV viral load. National goals emphasize …

Background Monitoring knowledge of HIV status among people living with HIV is essential
for an effective national HIV response. This study estimates progress and gaps in reaching …

The landmark HIV Prevention Trials Network (HPTN) 052 trial in HIV-discordant couples
demonstrated unequivocally that treatment with antiretroviral therapy (ART) substantially …

The scale-up of antiretroviral therapy (ART) is expected to raise adult life expectancy in
populations with high HIV prevalence. Using data from a population cohort of over 101,000 …

Background Regional and subtype-specific mutational patterns of HIV-1 transmitted drug
resistance (TDR) are essential for informing first-line antiretroviral (ARV) therapy guidelines …

Background To assess the effect of a combination strategy for prevention of human
immunodeficiency virus (HIV) on the incidence of HIV infection, we analyzed the association …

Antiretroviral drugs that inhibit viral replication were expected to reduce transmission of HIV
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …