Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation

E Sharifi, A Bigham, S Yousefiasl, M Trovato… - Advanced …, 2022 - Wiley Online Library
Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …

Pericyte loss in diseases

P Li, H Fan - Cells, 2023 - mdpi.com
Pericytes are specialized cells located in close proximity to endothelial cells within the
microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls …

Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury

S Bhowmick, V D'Mello, D Caruso, A Wallerstein… - Experimental …, 2019 - Elsevier
The blood-brain barrier (BBB) constitutes a neurovascular unit formed by microvascular
endothelial cells, pericytes, and astrocytes. Brain pericytes are important regulators of BBB …

Revisiting excitotoxicity in traumatic brain injury: from bench to bedside

D Baracaldo-Santamaría, DF Ariza-Salamanca… - Pharmaceutics, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …

Repeated closed-head mild traumatic brain injury-induced inflammation is associated with nociceptive sensitization

T Nguyen, N Nguyen, AG Cochran, JA Smith… - Journal of …, 2023 - Springer
Background Individuals who have experienced mild traumatic brain injuries (mTBIs) suffer
from several comorbidities, including chronic pain. Despite extensive studies investigating …

Traumatic brain injury-induced downregulation of Nrf2 activates inflammatory response and apoptotic cell death

S Bhowmick, V D'Mello, D Caruso… - Journal of molecular …, 2019 - Springer
Recent studies from our group and others have demonstrated that oxidative stress, Ca 2+
signaling, and neuroinflammation are major mechanisms contributing to post-traumatic …

Reactive gliosis in traumatic brain injury: a comprehensive review

Z Amlerova, M Chmelova, M Anderova… - Frontiers in Cellular …, 2024 - frontiersin.org
Traumatic brain injury (TBI) is one of the most common pathological conditions impacting the
central nervous system (CNS). A neurological deficit associated with TBI results from a …

Transforming growth factor-beta 1 signaling regulates neuroinflammation and apoptosis in mild traumatic brain injury

RK Patel, N Prasad, R Kuwar, D Haldar… - Brain, behavior, and …, 2017 - Elsevier
Mild traumatic brain injury (mTBI) is a low-level injury, which often remains undiagnosed,
and in most cases it leads to death and disability as it advances as secondary injury …

In Vitro Models of Traumatic Brain Injury: A Systematic Review

YH Wu, S Rosset, T Lee, M Dragunow, T Park… - Journal of …, 2021 - liebertpub.com
Traumatic brain injury (TBI) is a major public health challenge that is also the third leading
cause of death worldwide. It is also the leading cause of long-term disability in children and …

Colon‐Targeted Release of Gel Microspheres Loaded with Antioxidative Fullerenol for Relieving Radiation‐Induced Colon Injury and Regulating Intestinal Flora

C Wang, M Zhao, J Xie, H Wang… - Advanced Healthcare …, 2023 - Wiley Online Library
Radiation‐induced colitis is a serious clinical problem worldwide. However, the current
treatment options for this condition have limited efficacy and can cause side effects. To …