Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress
H Ehrenreich, M Gassmann, L Poustka… - …, 2023 - Wiley Online Library
Hypoxia is increasingly recognized as an important physiological driving force. A specific
transcriptional program, induced by a decrease in oxygen (O2) availability, for example …
transcriptional program, induced by a decrease in oxygen (O2) availability, for example …
[HTML][HTML] Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation
A Mrestani, K Lichter, AL Sirén, M Heckmann… - International Journal of …, 2023 - mdpi.com
Single-molecule localization microscopy (SMLM) greatly advances structural studies of
diverse biological tissues. For example, presynaptic active zone (AZ) nanotopology is …
diverse biological tissues. For example, presynaptic active zone (AZ) nanotopology is …
[PDF][PDF] Ultrastructural analysis of wild-type and RIM1α knockout active zones in a large cortical synapse
Rab3A-interacting molecule (RIM) is crucial for fast Ca 2+-triggered synaptic vesicle (SV)
release in presynaptic active zones (AZs). We investigated hippocampal giant mossy fiber …
release in presynaptic active zones (AZs). We investigated hippocampal giant mossy fiber …
[HTML][HTML] Endogenous tagging of Unc-13 reveals nanoscale reorganization at active zones during presynaptic homeostatic potentiation
S Dannhäuser, A Mrestani, F Gundelach… - Frontiers in Cellular …, 2022 - frontiersin.org
Neurotransmitter release at presynaptic active zones (AZs) requires concerted protein
interactions within a dense 3D nano-hemisphere. Among the complex protein mesh-work …
interactions within a dense 3D nano-hemisphere. Among the complex protein mesh-work …
[HTML][HTML] Visualizing presynaptic active zones and synaptic vesicles
M Heckmann, M Pauli - Frontiers in Synaptic Neuroscience, 2022 - frontiersin.org
The presynaptic active zone (AZ) of chemical synapses is a highly dynamic compartment
where synaptic vesicle fusion and neurotransmitter release take place. During evolution the …
where synaptic vesicle fusion and neurotransmitter release take place. During evolution the …
Active zone compaction in presynaptic homeostatic potentiation
A Mrestani, P Kollmannsberger, M Pauli, F Repp… - BioRxiv, 2019 - biorxiv.org
Brain function relies on neurotransmission which is stabilized by presynaptic homeostatic
potentiation (PHP). PHP operates on time scales ranging from minute-to life-long …
potentiation (PHP). PHP operates on time scales ranging from minute-to life-long …
Single-molecule time resolution in dilute liquids and live cells at the molecular scale: Constraints on the measurement time
Z Földes-Papp - American Journal of …, 2021 - journals.publicknowledgeproject.org
The research article is in continuation of previous theoretical work of the author and extends
this theory by defining limits in measurement times that should not be exceeded when one …
this theory by defining limits in measurement times that should not be exceeded when one …
Die Ultrastruktur von Aktiven Zonen in hippocampalen Moosfaserboutons
K Lichter - 2023 - opus.bibliothek.uni-wuerzburg.de
In Nervensystemen bedürfen Informationsweitergabe und Gedächtnisformation eines
präzisen Zusammenspiels von Synapsen in Zeit und Raum. Synaptische Transmission …
präzisen Zusammenspiels von Synapsen in Zeit und Raum. Synaptische Transmission …