The Role of Macrophages in Staphylococcus aureus Infection
GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …
Exploring the Role of Staphylococcus aureus in Inflammatory Diseases
H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …
play an extremely important role in a variety of diseases. This paper describes the types of …
Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies
J Clegg, E Soldaini, RM McLoughlin… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …
antibiotic resistance profile reinforces the need for new interventions like vaccines in …
Inside job: Staphylococcus aureus host-pathogen interactions
J Horn, K Stelzner, T Rudel, M Fraunholz - International Journal of Medical …, 2018 - Elsevier
Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of
diseases. Recent research established that once phagocytosed by neutrophils and …
diseases. Recent research established that once phagocytosed by neutrophils and …
Intracellular replication of Staphylococcus aureus in mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination
The success of Staphylococcus aureus as a pathogen is partly attributable to its ability to
thwart host innate immune responses, which includes resisting the antimicrobial functions of …
thwart host innate immune responses, which includes resisting the antimicrobial functions of …
Staphylococcus aureus RNAIII and Its Regulon Link Quorum Sensing, Stress Responses, Metabolic Adaptation, and Regulation of Virulence Gene Expression
Staphylococcus aureus RNAIII is one of the main intracellular effectors of the quorum-
sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding …
sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding …
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain
elusive. While the importance of cellular immunity has been shown in mice, T cell responses …
elusive. While the importance of cellular immunity has been shown in mice, T cell responses …
In or out: Phagosomal escape of Staphylococcus aureus
A Moldovan, MJ Fraunholz - Cellular microbiology, 2019 - Wiley Online Library
Staphylococcus aureus is internalised by host cells in vivo, and recent research results
suggest that the bacteria use this intracellularity to persist in the host and form a reservoir for …
suggest that the bacteria use this intracellularity to persist in the host and form a reservoir for …
Antibody–antibiotic conjugates: a novel therapeutic platform against bacterial infections
S Mariathasan, MW Tan - Trends in molecular medicine, 2017 - cell.com
Antibodies are potent components of the immune repertoire and have been successfully
exploited to treat bacterial infections. Recently an antibody–antibiotic conjugate (AAC) that …
exploited to treat bacterial infections. Recently an antibody–antibiotic conjugate (AAC) that …
The beclin 1 interactome: Modification and roles in the pathology of autophagy-related disorders
S Kaur, H Changotra - Biochimie, 2020 - Elsevier
Beclin 1 a yeast Atg6/VPS30 orthologue has a significant role in autophagy process
(Macroautophagy) and protein sorting. The function of beclin 1 depends on the interaction …
(Macroautophagy) and protein sorting. The function of beclin 1 depends on the interaction …