Purpose—Much has transpired since the last scientific statement on pediatric stroke was
published 10 years ago. Although stroke has long been recognized as an adult health …

Aim To review multiorgan involvement and management in children with Down syndrome
(DS). Methods A literature review of articles from 1980 to 2019 using the MEDLINE interface …

This clinical report is designed to assist the pediatrician in caring for the child, adolescent,
and family in whom a diagnosis of Down syndrome has been confirmed by chromosome …

Down syndrome (DS) is one of the most well-recognized genetic disorders. Persons with DS
are known to have a variety of co-morbid medical problems, affecting nearly all organ …

OBJECTIVE The optimal revascularization for pediatric moyamoya for reducing the
incidence of future stroke events remains to be determined. METHODS The authors …

Introduction: Moyamoya arteriopathy, which can be idiopathic or associated with sickle cell
disease, neurofibromatosis, Down syndrome, or cranial radiation therapy, is a progressive …

OBJECTIVE Phenotypic differences between moyamoya disease (MMD) and moyamoya
syndrome (MMS) remain unclear. The purpose of this study was to evaluate whether such …

Objective: To determine if elevated rates of autoimmune disease are present in children with
both Down syndrome and moyamoya disease given the high rates of autoimmune disease …

Summary Down Syndrome (Ds) is the most common chromosomal cause of intellectual
disability that results from triplication of chromosome 21 genes. Individuals with Ds …

Moyamoya, a rare angiographic finding, is characterized by chronic and progressive
stenosis at the terminal end of the internal carotid artery, followed by collateralization of the …