Cancer, cardiovascular disease, and infectious diseases are all global health threats. To
combat these diseases with gene therapies, adenovirus-based vectors have been …

In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

Adenoviruses are used extensively as gene transfer agents, both experimentally and
clinically. However, targeting of liver cells by adenoviruses compromises their potential …

Gene delivery vectors based on Adenoviral (Ad) vectors have enormous potential for the
treatment of both hereditary and acquired disease. Detailed structural analysis of the Ad …

Adenoviruses (Ads) are the most frequently used viral vectors in gene therapy and cancer
therapy. Obstacles to successful clinical application include accumulation of vector and …

Adenoviruses (Ad) are commonly used both experimentally and clinically, including
oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the …

Hepatocytes are a key target for gene therapy of inborn errors of metabolism as well as of
acquired diseases such as liver cancer and hepatitis. Gene transfer efficiency into …

Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing
goal in the field of clinical gene therapy. To achieve this, platform vectors must combine …

Adenoviruses represent exceptional candidates for wide-ranging therapeutic applications,
from vectors for gene therapy to oncolytics for cancer treatments. The first ever commercial …

The COVID-19 pandemic has had a heavy impact on global health and economy and
vaccination remains the primary way of controlling the infection. During the ongoing …