Accurate diagnosis for mild traumatic brain injury (mTBI) remains challenging, as prognosis
and return-to-play/work decisions are based largely on patient reports. Numerous …

Reviewed herein are contemporary neuroimaging methods that detect abnormalities
associated with mild traumatic brain injury (mTBI). Despite advances in demonstrating …

Background Blood biomarkers are valuable tools for elucidating complex cellular and
molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of …

To identify long-term effects of traumatic brain injury (TBI) on levels of plasma neuron-
derived exosome (NDE) protein biomarkers of cognitive impairment (CI), plasmas were …

Although mild traumatic brain injury (mTBI), or concussion, is not typically associated with
abnormalities on computed tomography (CT), it nevertheless causes persistent cognitive …

Objective Neuronal exosomes purified from peripheral blood samples have been proposed
as diagnostic tool in the setting of acute brain injury but never tested clinically. We …

Introduction Concussions are a major health concern as they cause significant acute
symptoms and in some athletes, long-term neurologic dysfunction. Diagnosis of concussion …

The long-term health effects of concussion and sub-concussive impacts in sport are
unknown. Growing evidence suggests both inflammation and neurodegeneration are pivotal …

Traumatic brain injury (TBI) most frequently occurs in pediatric patients and remains a
leading cause of childhood death and disability. Mild TBI (mTBI) accounts for nearly 75% of …

The association of military blast exposure and brain injury was first appreciated in World War
I as commotio cerebri, and later as shell shock. Similar injuries sustained in modern military …