Coumarins and coumarin-related compounds in pharmacotherapy of cancer
Cancer is one of the most common causes of disease-related deaths worldwide. Despite the
discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes …
discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes …
[HTML][HTML] Cancer hallmarks, biomarkers and breast cancer molecular subtypes
X Dai, L Xiang, T Li, Z Bai - Journal of cancer, 2016 - ncbi.nlm.nih.gov
Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …
Extracting insights from the shape of complex data using topology
This paper applies topological methods to study complex high dimensional data sets by
extracting shapes (patterns) and obtaining insights about them. Our method combines the …
extracting shapes (patterns) and obtaining insights about them. Our method combines the …
Deep learning-enabled breast cancer hormonal receptor status determination from base-level H&E stains
For newly diagnosed breast cancer, estrogen receptor status (ERS) is a key molecular
marker used for prognosis and treatment decisions. During clinical management, ERS is …
marker used for prognosis and treatment decisions. During clinical management, ERS is …
Evaluation of MCF10A as a reliable model for normal human mammary epithelial cells
Breast cancer is the most common cancer in women and a leading cause of cancer-related
deaths for women worldwide. Various cell models have been developed to study breast …
deaths for women worldwide. Various cell models have been developed to study breast …
Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the …
F Kamangar, GM Dores, WF Anderson - Journal of clinical oncology, 2006 - ascopubs.org
Efforts to reduce global cancer disparities begin with an understanding of geographic
patterns in cancer incidence, mortality, and prevalence. Using the GLOBOCAN (2002) and …
patterns in cancer incidence, mortality, and prevalence. Using the GLOBOCAN (2002) and …
Prognostic markers in triple‐negative breast cancer
EA Rakha, ME El‐Sayed, AR Green, AHS Lee… - Cancer, 2007 - Wiley Online Library
BACKGROUND. Triple‐negative breast cancer (estrogen receptor‐negative, progesterone
receptor‐negative, and HER2‐negative) is a high risk breast cancer that lacks the benefit of …
receptor‐negative, and HER2‐negative) is a high risk breast cancer that lacks the benefit of …
CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer
S Liu, J Lachapelle, S Leung, D Gao, WD Foulkes… - Breast cancer …, 2012 - Springer
Introduction Tumor infiltrating lymphocytes may indicate an immune response to cancer
development, but their significance remains controversial in breast cancer. We conducted …
development, but their significance remains controversial in breast cancer. We conducted …
[HTML][HTML] Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
CA Livasy, G Karaca, R Nanda, MS Tretiakova… - Modern pathology, 2006 - Elsevier
Microarray profiling of invasive breast carcinomas has identified five distinct subtypes of
tumors (luminal A, luminal B, normal breast-like, HER2 overexpressing, and basal-like) that …
tumors (luminal A, luminal B, normal breast-like, HER2 overexpressing, and basal-like) that …
Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes
Abstract Purpose: Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2
negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome …
negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome …