Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Fluorescent probes for lipid membranes: from the cell surface to organelles

AS Klymchenko - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Biomembranes are ubiquitous lipid structures that delimit the cell surface and
organelles and operate as platforms for a multitude of biomolecular processes. The …

Targeted solvatochromic fluorescent probes for imaging lipid order in organelles under oxidative and mechanical stress

DI Danylchuk, PH Jouard… - Journal of the American …, 2021 - ACS Publications
Biomembranes constitute a basis for all compartments of live cells, and therefore, the
monitoring of their lipid organization is essential for understanding cell status and activity …

Recent progresses in fluorescent probes for detection of polarity

H Xiao, P Li, B Tang - Coordination Chemistry Reviews, 2021 - Elsevier
Polarity, as a complex parameter, plays pivotal roles in chemistry and biology. Deviant
polarity change in different subcellular compartments is closely connected with diseases …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Fluorescent probes for the imaging of lipid droplets in live cells

H Tian Jr, AC Sedgwick, HH Han, S Sen… - Coordination Chemistry …, 2021 - Elsevier
Lipid droplets (LDs) are cellular organelles that are essential for maintaining lipid and
energy homeostasis. Once regarded as merely inert fat particles, they are now recognized …

Development of near-infrared mitochondrial polarity fluorescent probe for evaluating mitophagy in mice heart and potential cancer diagnosis

T Zhang, F Huo, W Zhang, F Cheng, C Yin - Chemical Engineering Journal, 2022 - Elsevier
Mitophagy is a process that selectively removes excess or damaged mitochondria, and
regulates the number of mitochondria in the cell to maintain the normal mitochondrial …

Advanced functional fluorescent probes for cell plasma membranes

M Collot, S Pfister, AS Klymchenko - Current Opinion in Chemical Biology, 2022 - Elsevier
Imaging the plasma membrane (PM) by fluorescence techniques using molecular
fluorescent probes enable cell segmentation, studying membrane organization and …

Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity

W Teo, AV Caprariello, ML Morgan… - Proceedings of the …, 2021 - National Acad Sciences
The molecular composition of myelin membranes determines their structure and function.
Even minute changes to the biochemical balance can have profound consequences for …

[HTML][HTML] Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts

A Honda, M Nozumi, Y Ito, R Natsume, A Kawasaki… - Cell Reports, 2023 - cell.com
Fatty acids have long been considered essential to brain development; however, the
involvement of their synthesis in nervous system formation is unclear. We generate mice …