Cell–cell communication: new insights and clinical implications

J Su, Y Song, Z Zhu, X Huang, J Fan, J Qiao… - Signal Transduction and …, 2024 - nature.com
Multicellular organisms are composed of diverse cell types that must coordinate their
behaviors through communication. Cell–cell communication (CCC) is essential for growth …

Tunneling nanotubes: The intercellular conduits contributing to cancer pathogenesis and its therapy

PK Melwani, BN Pandey - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …

Pulsed laser assisted high-throughput intracellular delivery in hanging drop based three dimensional cancer spheroids

P Gupta, S Kar, A Kumar, FG Tseng, S Pradhan… - Analyst, 2021 - pubs.rsc.org
Targeted intracellular delivery of biomolecules and therapeutic cargo enables the controlled
manipulation of cellular processes. Laser-based optoporation has emerged as a versatile …

The intercellular communications mediating radiation-induced bystander effects and their relevance to environmental, occupational, and therapeutic exposures

M Buonanno, G Gonon, BN Pandey… - International journal of …, 2023 - Taylor & Francis
Purpose The assumption that traversal of the cell nucleus by ionizing radiation is a
prerequisite to induce genetic damage, or other important biological responses, has been …

Tunneling nanotubes mediate the expression of senescence markers in mesenchymal stem/stromal cell spheroids

J Whitehead, J Zhang, JN Harvestine… - Stem Cells, 2020 - academic.oup.com
The therapeutic potential of mesenchymal stem/stromal cells (MSCs) is limited by acquired
senescence following prolonged culture expansion and high-passage numbers. However …

Molecular, morphological and functional properties of tunnelling nanotubes between normal and cancer urothelial cells: New insights from the in vitro model …

N Resnik, D Baraga, P Glažar… - Frontiers in Cell and …, 2022 - frontiersin.org
Tunnelling nanotubes (TNTs) are membranous connections that represent a unique type of
intercellular communication in different cell types. They are associated with cell physiology …

Laser-assisted optoporation of cells and tissues–a mini-review

H Schneckenburger - Biomedical Optics Express, 2019 - opg.optica.org
Laser microbeam techniques are presented, which permit the introduction of molecules or
small particles into living cells. Possible mechanisms− including photochemical …

Macrophage conditioned medium induced cellular network formation in MCF-7 cells through enhanced tunneling nanotube formation and tunneling nanotube …

P Patheja, K Sahu - Experimental cell research, 2017 - Elsevier
Infiltrating macrophages in tumor microenvironment, through their secreted cytokines and
growth factors, regulate several processes of cancer progression such as cancer cell …

Role of tunneling nanotubes in the nervous system

O Tarasiuk, A Scuteri - International Journal of Molecular Sciences, 2022 - mdpi.com
Cellular communication and the transfer of information from one cell to another is crucial for
cell viability and homeostasis. During the last decade, tunneling nanotubes (TNTs) have …

Direct observation of tunneling nanotubes within human mesenchymal stem cell spheroids

J Zhang, J Whitehead, Y Liu, Q Yang… - The Journal of …, 2018 - ACS Publications
Tunneling nanotubes (TNTs) play an important role in cell–cell communication. TNTs have
been predominantly reported among cells in monolayer culture. Using various imaging …