The hypothalamic neuropeptide oxytocin (OT), which is evolutionarily conserved among
different species throughout the animal kingdom, is a key modulator of a variety of socio …

The paraventricular nucleus (PVN) is a highly organized structure of the hypothalamus that
has a key role in regulating cardiovascular and osmotic homeostasis. Functionally, the PVN …

Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …

The hypothalamus is key in the control of energy balance. However, strategies targeting
hypothalamic neurons have failed to provide viable options to treat most metabolic diseases …

Corticotropin-releasing factor (CRF) neurons in the hypothalamic paraventricular nucleus
(PVN) initiate hypothalamic–pituitary–adrenal axis activity through the release of CRF into …

Although many studies have addressed the regulatory circuits affecting neuronal activities,
local non-synaptic mechanisms that determine neuronal excitability remain unclear. Here …

The prosocial neuropeptide oxytocin is being developed as a potential treatment for various
neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using …

The hypothalamic paraventricular nucleus (PVN) integrates preautonomic and
neuroendocrine control of energy homeostasis, fluid balance, and the stress response. We …

The suprachiasmatic nucleus (SCN) controls the circadian rhythm of melatonin synthesis in
the mammalian pineal gland by a multisynaptic pathway including, successively …

The prevalence of metabolic disorders, including type 2 diabetes mellitus, continues to
increase worldwide. Although newer and more advanced therapies are available, current …