The unprecedented use of antibiotics that led to development of resistance affect human
health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases …

Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …

Antimicrobial resistance in clinically important microbes has emerged as an unmet
challenge in global health. Extensively drug-resistant bacterial pathogens have cropped up …

Drug efflux protein complexes confer multidrug resistance on bacteria by transporting a wide
spectrum of structurally diverse antibiotics. Moreover, organisms can only acquire resistance …

Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …

Simple Summary Multidrug-resistant bacterial infections, especially that caused by Gram-
negative bacteria, have posed serious health issues worldwide. Bacteria have different …

The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

There is urgent need for new therapeutic strategies to fight the global threat of antibiotic
resistance. The focus of this Perspective is on chemical agents that target the most common …

Inappropriate and injudicious use of antimicrobial drugs in human health, hygiene,
agriculture, animal husbandry and food industries has contributed significantly to rapid …

A global upsurge in emergence and spread of antibiotic resistance (ABR) in bacterial
populations is a serious threat for human health. Unfortunately, ABR is no longer confined to …