Multi-parameter flow cytometry, molecular genetics, and cytogenetic studies have all
contributed to new classification of leukemia. In this review we discuss immunophenotypic …

BACKGROUND AND OBJECTIVE: The diagnosis of acute leukemias (AL) requires a
multiparametric approach in order to apply risk-adapted therapeutic protocols and …

BACKGROUND AND OBJECTIVES: Recent reports suggest that CD4 (+)/CD56 (+)/lineage (-
) hematopoietic neoplasias are aggressive types of malignancies involving …

The ability of 4-color flow cytometry (FC) to help identify myelodysplastic syndromes (MDSs)
was evaluated in 124 bone marrow aspirates from unselected patients with unexplained …

PURPOSE: Blast expression of CD56 is frequent in patients with t (8; 21)(q22; q22) acute
myeloid leukemia and is associated with an inferior outcome. The expression of CD56 has …

Context.—The diagnosis of myeloproliferative disorders (MPDs) and myelodysplastic
syndromes (MDSs) has historically relied on combining clinical information with the …

Published data on flow cytometry (FCM) in diagnosing myelodysplastic syndromes (MDS)
varies greatly in analytic methods and interpretational approaches. We tested the diagnostic …

As hematopoietic cells proceed in differentiation from stem cells to committed progenitors to
later stage mature forms, they undergo a sequence of morphologic, immunophenotypic, and …

BACKGROUND AND OBJECTIVE: The myelodysplastic syndromes (MDS) are clonal stem
cell disorders associated with a variety of abnormalities of mature and maturing cells …

BACKGROUND AND OBJECTIVES. CD56 antigen expression has been reported in several
hematologic malignancies. In acute myeloid leukemia (AML) M2 with t (8; 21) and acute …