Mitochondrial dysfunctions are among the main hallmarks of several brain diseases,
including ischemic stroke. An insufficient supply of oxygen and glucose in brain cells …

To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …

Background Our previous study reports the causal role of high mobility group box 1
(HMGB1) in the development of depression; and we find glycyrrhizic acid (GZA) can be a …

Background Ischemic stroke is a severe neurological disorder that affected millions of
people worldwide. Neuro-inflammation and apoptosis play an essential role in the …

The current research aimed to assess the impacts of Minocycline on varicocele‐induced
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …

Tanshinone IIA, a fat-soluble diterpenoid isolated from Salvia miltiorrhiza Bunge, has been
shown to attenuate the cerebral ischemic injury. The aim of this study was to examine the …

Methamphetamine (METH) is a highly addictive psychostimulant that causes significant
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …

Objectives Oxidative stress and inflammation have a critical role in the pathogenesis of
ischaemic stroke. Alpha-pinene is a monoterpenoid molecule with anti-inflammatory and …

Background Morbidity and mortality remain high for ischemic stroke victims, and at present
these patients lack effective neuroprotective agents, which improve the cure rate. In recent …

Abstract Context Puerarin (Pue) and tanshinone IIA (Tan IIA) are often used in combination
in the treatment of cerebrovascular diseases. Objective To investigate the neuroprotective …