[HTML][HTML] Different roles of mitochondria in cell death and inflammation: Focusing on mitochondrial quality control in ischemic stroke and reperfusion
Mitochondrial dysfunctions are among the main hallmarks of several brain diseases,
including ischemic stroke. An insufficient supply of oxygen and glucose in brain cells …
including ischemic stroke. An insufficient supply of oxygen and glucose in brain cells …
[HTML][HTML] Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review
Y Naderi, Y Panahi, GE Barreto… - Neural regeneration …, 2020 - journals.lww.com
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons
B Wang, X Huang, X Pan, T Zhang, C Hou… - Brain, behavior, and …, 2020 - Elsevier
Background Our previous study reports the causal role of high mobility group box 1
(HMGB1) in the development of depression; and we find glycyrrhizic acid (GZA) can be a …
(HMGB1) in the development of depression; and we find glycyrrhizic acid (GZA) can be a …
Alpha-pinene exerts neuroprotective effects via anti-inflammatory and anti-apoptotic mechanisms in a rat model of focal cerebral ischemia-reperfusion
M Khoshnazar, S Parvardeh, MR Bigdeli - Journal of Stroke and …, 2020 - Elsevier
Background Ischemic stroke is a severe neurological disorder that affected millions of
people worldwide. Neuro-inflammation and apoptosis play an essential role in the …
people worldwide. Neuro-inflammation and apoptosis play an essential role in the …
Minocycline can reduce testicular apoptosis related to varicocele in male rats
M Shokoohi, A Khaki, A Roudi Rasht Abadi… - Andrologia, 2022 - Wiley Online Library
The current research aimed to assess the impacts of Minocycline on varicocele‐induced
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …
[HTML][HTML] Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway
Z Song, J Feng, Q Zhang, S Deng, D Yu… - Frontiers in …, 2021 - frontiersin.org
Tanshinone IIA, a fat-soluble diterpenoid isolated from Salvia miltiorrhiza Bunge, has been
shown to attenuate the cerebral ischemic injury. The aim of this study was to examine the …
shown to attenuate the cerebral ischemic injury. The aim of this study was to examine the …
Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling …
T Lwin, JL Yang, S Ngampramuan, K Viwatpinyo… - Progress in Neuro …, 2021 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant that causes significant
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …
Attenuating effect of α-pinene on neurobehavioural deficit, oxidative damage and inflammatory response following focal ischaemic stroke in rat
M Khoshnazar, MR Bigdeli, S Parvardeh… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Oxidative stress and inflammation have a critical role in the pathogenesis of
ischaemic stroke. Alpha-pinene is a monoterpenoid molecule with anti-inflammatory and …
ischaemic stroke. Alpha-pinene is a monoterpenoid molecule with anti-inflammatory and …
[HTML][HTML] Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway
K Fu, M Chen, H Zheng, C Li, F Yang… - Translational …, 2021 - degruyter.com
Background Morbidity and mortality remain high for ischemic stroke victims, and at present
these patients lack effective neuroprotective agents, which improve the cure rate. In recent …
these patients lack effective neuroprotective agents, which improve the cure rate. In recent …
Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury in rats via activating the Nrf2/ARE signalling pathway
Q Miao, R Wang, X Sun, S Du, L Liu - Pharmaceutical biology, 2022 - Taylor & Francis
Abstract Context Puerarin (Pue) and tanshinone IIA (Tan IIA) are often used in combination
in the treatment of cerebrovascular diseases. Objective To investigate the neuroprotective …
in the treatment of cerebrovascular diseases. Objective To investigate the neuroprotective …