Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Traditionally, genetics and lifestyle are considered as main determinants of aging-
associated pathological conditions. Accumulating evidence, however, suggests that risk of …

The go-to resource for assessing and predicting functional abilities in persons with brain
injury or cognitive decline has now been revised and expanded to reflect significant …

Obesity is an increasing health concern related to many metabolic disorders, including
metabolic syndrome, diabetes type 2 and cardiovascular diseases. Many studies suggest …

According to the World Health Organization, the population of over 60 will double in the next
30 years in the developed countries, which will enforce a further raise of the retirement age …

Longevity is mainly conditioned by genetic, epigenetic and environmental factors. Different
genetic modifications seem to be positively associated to longevity, including SNPs in …

Numerous human chronic pathological conditions depend on epigenetic modifications
induced by environmental triggers throughout sensitive stages early in development …

Obesity caused by excessive fat accumulation in adipocytes is a growing global problem
and is a major contributing risk factor for many chronic metabolic diseases. There is …

Type 2 diabetes (T2D) is commonly regarded as a disease originating from lifestyle‐related
factors and typically occurring after the age of 40. There is, however, consistent experimental …

Aging is accompanied by alterations in the body with time-related to decline of physiological
integrity and functionality process, responsible for increasing diseases and vulnerability to …