Informing deep neural networks by multiscale principles of neuromodulatory systems
Our brains have evolved the ability to configure and adapt their processing states to match
the unique challenges of acting and learning in diverse environments and behavioral …
the unique challenges of acting and learning in diverse environments and behavioral …
The mesencephalic locomotor region: multiple cell types, multiple behavioral roles, and multiple implications for disease
D Ryczko - The Neuroscientist, 2024 - journals.sagepub.com
The mesencephalic locomotor region (MLR) controls locomotion in vertebrates. In humans
with Parkinson disease, locomotor deficits are increasingly associated with decreased …
with Parkinson disease, locomotor deficits are increasingly associated with decreased …
[HTML][HTML] A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement
Motor behaviors are often planned long before execution but only released after specific
sensory events. Planning and execution are each associated with distinct patterns of motor …
sensory events. Planning and execution are each associated with distinct patterns of motor …
[HTML][HTML] Modulation of motor behavior by the mesencephalic locomotor region
D Dautan, A Kovács, T Bayasgalan, MA Diaz-Acevedo… - Cell reports, 2021 - cell.com
The mesencephalic locomotor region (MLR) serves as an interface between higher-order
motor systems and lower motor neurons. The excitatory module of the MLR is composed of …
motor systems and lower motor neurons. The excitatory module of the MLR is composed of …
Rapid effects of vagus nerve stimulation on sensory processing through activation of neuromodulatory systems
After sensory information is encoded into neural signals at the periphery, it is processed
through multiple brain regions before perception occurs (ie, sensory processing). Recent …
through multiple brain regions before perception occurs (ie, sensory processing). Recent …
Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies
Assimilation of novel strategies into a consolidated action repertoire is a crucial function for
behavioral adaptation and cognitive flexibility. Acetylcholine in the striatum plays a pivotal …
behavioral adaptation and cognitive flexibility. Acetylcholine in the striatum plays a pivotal …
Ten key reasons for continuing research on pharmacotherapy for post-stroke aphasia
ML Berthier - Aphasiology, 2021 - Taylor & Francis
Background: Aphasia is a devastating disorder occurring in more than 30% of stroke victims.
Speech and language therapy (SLT) is the treatment of choice for post-stroke aphasia (PSA) …
Speech and language therapy (SLT) is the treatment of choice for post-stroke aphasia (PSA) …
Brain‐wide mapping of inputs to the mouse lateral posterior (LP/pulvinar) thalamus–anterior cingulate cortex network
YN Leow, B Zhou, HA Sullivan… - Journal of …, 2022 - Wiley Online Library
The rodent homolog of the primate pulvinar, the lateral posterior (LP) thalamus, is
extensively interconnected with multiple cortical areas. While these cortical interactions can …
extensively interconnected with multiple cortical areas. While these cortical interactions can …
[HTML][HTML] EEG, MEG and neuromodulatory approaches to explore cognition: Current status and future directions
Neural oscillations and their association with brain states and cognitive functions have been
object of extensive investigation over the last decades. Several electroencephalography …
object of extensive investigation over the last decades. Several electroencephalography …
Mapping cholinergic synaptic loss in Parkinson's disease: An [18F] FEOBV PET case-control study
Background: Cholinergic degeneration is strongly associated with cognitive decline in
patients with Parkinson's disease (PD) but may also cause motor symptoms and olfactory …
patients with Parkinson's disease (PD) but may also cause motor symptoms and olfactory …