Human cytochrome P450 1A2 (CYP1A2) is one of the major CYPs in the liver (&sim13%)
and metabolizes about 20% of clinically used drugs. CYP1A2 is a 515-residue protein with a …

Abstract Ethnopharmacological relevance Moutan Cortex (MC), commonly known as “Mu
dan pi”, refers to the dried root bark of Paeonia x suffruticosa Andrews and is broadly used …

Despite great advances in therapies observed during the last decades, heart failure (HF)
remained a major health problem in western countries. In order to further improve symptoms …

Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and
inflammation have been proved in the development of MTX toxicity. Paeonol is a natural …

Cigarette smoking causes persistent lung inflammation that is mainly regulated by redox‐
sensitive pathways. We have previously reported that cigarette smoke (CS) activates …

Inflammation and oxidative stress play important roles in the pathogenesis of
neurodegenerative disorders such as stroke, traumatic injury, Parkinson disease, and …

Ethnopharmacological relevance Taraxasterol was isolated from the Chinese medicinal
herb Taraxacum officinale which has been frequently used as a remedy for inflammatory …

In this study, we evaluated the immunomodulatory effects of xanthan gum (XG) in RAW264.
7 macrophages and the underlying molecular mechanisms. We used scanning electron …

Ethnopharmacological relevance A herbal formula (RL) consisting of Rosae Multiflorae
Fructus (Yingshi) and Lonicerae Japonicae Flos (Jinyinhua) has been traditionally used to …

Paeonol, the main active component isolated from the root of Paeonia suffruticosa, has been
reported to have anti-inflammatory properties. However, the effects of paeonol on …