A typical output of a metabolomic experiment is a peak table corresponding to the intensity
of measured signals. Peak table processing, an essential procedure in metabolomics, is …

Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …

Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Accumulation of somatic mutations in the mitochondrial genome (mtDNA) has long been
proposed as a possible mechanism of mitochondrial and tissue dysfunction that occurs …

Acute kidney injury (AKI) is a prevalent condition in critically ill patients that is often
associated with significant morbidity and mortality. As the lack of effective early diagnosis …

Cardiovascular disease (CVD) is a group of systemic disorders threatening human health
with complex pathogenesis, among which mitochondrial energy metabolism reprogramming …

The goal of this study is to identify a signature of bioenergetic and functional markers in the
muscles of individuals with Parkinson's disease (PD). Quantitative physiological properties …

The endoplasmic reticulum (ER) plays a key role in the regulation of protein folding, lipid
synthesis, calcium homeostasis, and serves as a primary site of sphingolipid biosynthesis …

Background Diabetes mellitus (DM)-related corneal epithelial dysfunction is a severe ocular
disorder; however, the effects of nicotinamide mononucleotide (NMN) on high-glucose (HG) …