The role of vitamins in neurodegenerative disease: An update
SN Rai, P Singh, HWM Steinbusch, E Vamanu… - Biomedicines, 2021 - mdpi.com
Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions
A Dovonou, C Bolduc, V Soto Linan, C Gora… - Translational …, 2023 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
[HTML][HTML] Disease model organism for Parkinson disease: Drosophila melanogaster
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
selective and progressive loss of dopaminergic neurons. Genetic and environmental risk …
selective and progressive loss of dopaminergic neurons. Genetic and environmental risk …
Association study of DNAJC13, UCHL1, HTRA2, GIGYF2, and EIF4G1 with Parkinson's disease
Rare mutations in genes originally discovered in multigenerational families have been
associated with increased risk of Parkinson's disease (PD). The involvement of rare variants …
associated with increased risk of Parkinson's disease (PD). The involvement of rare variants …
Exploration of the Role of Vitamins in Preventing Neurodegenerative Diseases: Comprehensive Review on Preclinical and Clinical Findings
Neurodegenerative diseases (NDDs) are a multifaceted and heterogeneous group of
complex diseases. Unfortunately, a cure for these conditions has yet to be found, but there …
complex diseases. Unfortunately, a cure for these conditions has yet to be found, but there …
Therapeutic Potential of Polyscias fruticosa (L.) Harms Leaf Extract for Parkinson's Disease Treatment by Drosophila melanogaster Model
HT Ly, TTH Nguyen, VM Le, BT Lam… - Oxidative medicine …, 2022 - Wiley Online Library
Parkinson's disease (PD) is characterized by progressive locomotive defects and loss of
dopaminergic neurons. Polyscias fruticosa leaves are used by Vietnamese as herbal …
dopaminergic neurons. Polyscias fruticosa leaves are used by Vietnamese as herbal …
[HTML][HTML] A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake
FM Cerqueira, S von Stockum, M Giacomello, I Goliand… - Redox biology, 2020 - Elsevier
UCH-L1 is a deubiquitinating enzyme (DUB), highly abundant in neurons, with a sub-
cellular localization dependent on its farnesylation state. Despite UCH-L1′ s association …
cellular localization dependent on its farnesylation state. Despite UCH-L1′ s association …
Age-associated glia remodeling and mitochondrial dysfunction in neurodegeneration: antioxidant supplementation as a possible intervention
Aging induces substantial remodeling of glia, including density, morphology, cytokine
expression, and phagocytic capacity. Alterations of glial cells, such as hypertrophy of …
expression, and phagocytic capacity. Alterations of glial cells, such as hypertrophy of …
[HTML][HTML] Progress in Parkinson's disease animal models of genetic defects: Characteristics and application
C Zhang, S Chen, X Li, Q Xu, Y Lin, F Lin… - Biomedicine & …, 2022 - Elsevier
Parkinson's disease (PD) is the second major progressive neurodegenerative disease,
which critically impacts patients' quality of life. Based on genetics, animal models of genetic …
which critically impacts patients' quality of life. Based on genetics, animal models of genetic …