XIAP, X-linked inhibitor of apoptosis protein, is a member of the inhibitor of apoptosis protein
(IAP) family known for its important conserved inhibitory effect on caspase activity. Since the …

Alimentary tract (AT) mucositis can be a major problem for patients undergoing cancer
treatment. It has significant clinical and economic consequences and is a major factor that …

Background & Aims Despite remarkable advances in treatment, most patients with
hepatocellular carcinoma (HCC) respond poorly to anti-programmed cell death 1 (anti-PD1) …

Currently, there is no effective therapy for metastatic breast cancer after surgery, radiation,
and chemotherapy have been used against the primary tumor. Because curcumin …

MicroRNAs (miRNAs) as modulators of gene expression have been described to display
both tumor-promoting and tumor-suppressive functions. Although their role has been studied …

Lack of molecular targets in estrogen receptor-negative (ER-negative) breast cancer is a
major therapeutic hurdle. We studied NF-κB activation in human breast tumors and in …

PKC family consist of a number of serine-threonine kinases which are divided into three
groups based on their activating factors. PKCs have been linked to carcinogenesis since …

The nuclear factor κB (NFκB) superfamily of eukaryotic transcription factors plays an
important role in carcinogenesis. NF-κB and its regulators are linked to various signal …

MicroRNAs post-transcriptionally regulate gene expression and thereby contribute to the
modulation of numerous complex and disease-relevant cellular phenotypes, including cell …

Abstract In the United States there are 225,000 new cases of invasive breast cancer
annually, and at least 50,000 women are diagnosed with ductal carcinoma in situ (DCIS) …