[HTML][HTML] Saponins in cancer treatment: Current progress and future prospects

OO Elekofehinti, O Iwaloye, F Olawale, EO Ariyo - Pathophysiology, 2021 - mdpi.com
Saponins are steroidal or triterpenoid glycoside that is distinguished by the soap-forming
nature. Different saponins have been characterized and purified and are gaining attention in …

[HTML][HTML] Saponins from Chinese medicines as anticancer agents

XH Xu, T Li, CMV Fong, X Chen, XJ Chen, YT Wang… - Molecules, 2016 - mdpi.com
Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various
pharmacological effects against mammalian diseases. To promote the research and …

Natural products targeting tumour angiogenesis

X Lu, LJ Friedrich, T Efferth - British journal of pharmacology, 2023 - Wiley Online Library
Tumour angiogenesis is the formation of new blood vessels to support the growth of a
tumour. This process is critical for tumour progression and metastasis, making it an attractive …

[HTML][HTML] A Potential Biofertilizer—Siderophilic Bacteria Isolated From the Rhizosphere of Paris polyphylla var. yunnanensis

Y Wang, G Zhang, Y Huang, M Guo, J Song… - Frontiers in …, 2022 - frontiersin.org
The increasing demands for crop production have become a great challenge while people
also realizing the significance of reductions in synthetic chemical fertilizer use. Plant growth …

[HTML][HTML] Inhibiting angiogenesis by anti-cancer saponins: from phytochemistry to cellular signaling pathways

MB Majnooni, S Fakhri, SM Ghanadian, G Bahrami… - Metabolites, 2023 - mdpi.com
Saponins are one of the broadest classes of high-molecular-weight natural compounds,
consisting mainly of a non-polar moiety with 27 to 30 carbons and a polar moiety containing …

[HTML][HTML] Bioactive secondary metabolites in Paris polyphylla Sm. and their biological activities: A review

CB Thapa, MR Paudel, HD Bhattarai, KK Pant… - Heliyon, 2022 - cell.com
Paris polyphylla Sm. is an important medicinal plant used to treat a variety of diseases
through traditional medicine systems such as Ayurveda, Tibetan traditional medicines …

[HTML][HTML] Molecularly Characterized Solvent Extracts and Saponins from Polygonum hydropiper L. Show High Anti-Angiogenic, Anti-Tumor, Brine Shrimp, and …

M Ayaz, M Junaid, F Ullah, A Sadiq, F Subhan… - Frontiers in …, 2016 - frontiersin.org
Polygonum hydropiper is used as anti-cancer and anti-rheumatic agent in folk medicine.
This study was designed to investigate the anti-angiogenic, anti-tumor, and cytotoxic …

Anti-cancer effects of Polyphyllin I: An update in 5 years

Y Tian, GY Gong, LL Ma, ZQ Wang, D Song… - Chemico-Biological …, 2020 - Elsevier
Chong-lou, the rhizome of Paris polyphylla, has been used in herbal regimes to treat
parotitis, mastitis and certain malignant tumors for thousands of years in traditional medicine …

[HTML][HTML] Paris saponin I induces apoptosis via increasing the Bax/Bcl‑2 ratio and caspase‑3 expression in gefitinib‑resistant non‑small cell lung cancer in vitro and in …

H Jiang, PJ Zhao, D Su, J Feng… - Molecular Medicine …, 2014 - spandidos-publications.com
Polyphyllins, a major component of Rhizoma paridis, have been extensively used in non‑
small cell lung cancer (NSCLC). The aim of the present study was to evaluate the effects of …

Traditional Uses, Active Ingredients, and Biological Activities of Paris polyphylla Smith: A Comprehensive Review of an Important Himalayan Medicinal Plant

JM Rawat, S Pandey, B Rawat, N Rai… - Journal of …, 2023 - Wiley Online Library
Paris polyphylla Smith (family: Melanthiaceae), a high‐value medicinal herb endemic to the
Himalayan region, has drawn much attention recently due to its immense use in the …