Fungal pathogens are a severe public health problem. The leading causative agents of
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …

Highlights•Fungi have a serious impact on human health, causing millions of deaths
worldwide.•Scientific advances have enabled the discovery of novel antifungals.•This review …

Protein kinases are critical regulatory proteins in both prokaryotes and eukaryotes.
Accordingly, protein kinases represent a common drug target for a wide range of human …

Pathogenic fungi are an increasing public health concern. The emergence of antifungal
resistance coupled with the scarce antifungal arsenal highlights the need for novel …

Candida albicans is a leading cause of mycotic infection. The ability to transition between
yeast and filamentous forms is critical to C. albicans virulence and complex signaling …

Candida albicans is a major fungal pathogen of humans that can cause serious systemic
infections in vulnerable immunocompromised populations. One of its virulence attributes is …

Candida albicans is an opportunistic human fungal pathogen and a member of the mucosal
microbiota. To survive in the host and cause disease, C. albicans utilizes several virulence …

Candida albicans is a formidable fungal pathogen with a mortality rate of~ 40%. One of its
virulence attributes is its capacity to transition between yeast and filaments, but our …