A growing body of evidence indicates that, over the course of evolution of the immune
system, arginine has been selected as a node for the regulation of immune responses. An …

Background Infection after surgery and trauma is a major cause of increased morbidity,
mortality, and cost. Alterations of the hosts immune system following these insults is believed …

For many years, dietary arginine supplementation, often combined with other substances,
has been used as a mechanism to boost the immune system. Considerable controversy …

Nonessential amino acids are synthesized de novo and therefore not diet dependent. In
contrast, essential amino acids must be obtained through nutrition since they cannot be …

Purpose: The source of glioblastoma (GBM)-associated immunosuppression remains
multifactorial. We sought to clarify and therapeutically target myeloid cell–derived peripheral …

Arginine availability, arginase, and the immune response : Current Opinion in Clinical Nutrition
& Metabolic Care Arginine availability, arginase, and the immune response : Current Opinion …

Objective: To explore the hypothesis that decreased arginine availability by myeloid-derived
suppressor cells (MDSCs) is a cause of T-cell dysfunction after physical injury (PI) …

Arginine functions in the body as a free amino acid, a component of most proteins, and the
substrate for several non-protein, nitrogen-containing compounds, many of which function in …

Arginine supplementation has been identified as advantageous in experimental wound
healing. However, the mechanisms underlying this beneficial effect in tissue repair remain …

Background. The expression of human leukocyte antigen (HLA)-G during allogeneic
recognition is associated with better graft acceptance. The inhibitory receptor …