Antipsychotics represent the mainstay of schizophrenia pharmacological therapy, and their
role has been expanded in the last years to mood disorders treatment. Although introduced …

Many hypothesis have tried to explain the aetiology of schizophrenia, the abnormal
neurodevelopmental hypothesis is one of the most widely acknowledged and is based on …

Antipsychotic drugs are the primary treatment for psychosis, yet individual response to their
administration remains variable. At present, no biological predictors of response exist to …

BackgroundAlterations of cortical thickness have been shown in imaging studies of
schizophrenia but it is unclear to what extent they are related to disease phenotype …

The findings about the progressive brain changes in schizophrenia are controversial, and
the potential confounding effect of antipsychotics on brain structure is still under debate. The …

Although antipsychotic drugs are mainly used for treating schizophrenia, they are widely
used for treating various psychiatric diseases in adults, the elderly, adolescents and even …

BackgroundLoss of cortical volume in frontotemporal regions occurs in patients with first-
episode psychosis (FEP) and longitudinal studies have reported progressive brain volume …

Abstract Background and Hypothesis Early prediction of treatment response to
antipsychotics in schizophrenia remains a challenge in clinical practice. This study aimed to …

The association of antipsychotic medication with abnormal brain morphometry in
schizophrenia remains uncertain. This study investigated subcortical morphometric changes …

Electroconvulsive therapy (ECT) is a rapid and highly effective treatment option for treatment-
resistant major depressive disorder (TRD). The neural mechanisms underlying such …