Identifying Plasmodium P36 and P52 antigens for coadministration with circumsporozoite protein to enhance vaccine efficacy

N Yadav, AC Kalata, RA Reynolds, A Raappana… - npj Vaccines, 2024 - nature.com
Vaccines targeting the complex pre-erythrocytic stage of Plasmodium parasites may benefit
from the inclusion of multiple antigens. However, discerning protective effects can be difficult …

Mosquito bites and stage-specific antibody responses against Plasmodium falciparum in southern Ghana

SS Kwapong, KK Asare, KA Kusi, F Pappoe, N Ndam… - Malaria Journal, 2023 - Springer
Background The human host elicits specific immune responses after exposure to various life
stages of the malaria parasite as well as components of mosquito saliva injected into the …

Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2Kb Offer New Options To Combat Cryptosporidiosis

Y Wang, M Gao, X Li, W Zhu, M Zhao, J Li, X Liu, L Cao… - Mbio, 2023 - Am Soc Microbiol
Cryptosporidium parvum has gained much attention as a major cause of diarrhea in the
world, particularly in those with compromised immune systems. The data currently available …

Plasmodium Circumsporozoite Protein Enhances the Efficacy of Gefitinib in Lung Adenocarcinoma Cells by Inhibiting Autophagy via Proteasomal Degradation of …

X Lu, J Zhang, YQ Li, QX Liu, D Zhou… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: Almost all lung adenocarcinoma (LUAD) patients with EGFR mutant will
develop resistance to EGFR-TKIs, which limit the long-term clinical application of these …

Conservation of S20 as an Ineffective and Disposable IFNγ-Inducing Determinant of Plasmodium Sporozoites Indicates Diversion of Cellular Immunity

C Hon, J Friesen, A Ingmundson, D Scheppan… - Frontiers in …, 2021 - frontiersin.org
Despite many decades of research to develop a malaria vaccine, only one vaccine
candidate has been explored in pivotal phase III clinical trials. This candidate subunit …

Sex-sorting Aedes aegypti for sterile insect technique (SIT) by knocking down four different gene targets, expressed in the guts of female larvae

S Felix - 2023 - mspace.lib.umanitoba.ca
Mosquitoes are vectors for diseases that affect approximately 0.7 billion people globally.
Most of these diseases have a high incidence in tropical often developing countries, where …

[PDF][PDF] Mosquito bites and stages specific antibody responses against Plasmodium falciparum in southern Ghana

LE Amoah, KA Kusi - academia.edu
Background The human host elicits specific immune responses after exposure to various life
stages of the malaria parasite as well as components of mosquito saliva injected into the …