Sodium benzoate—Harmfulness and potential use in therapies for disorders related to the nervous system: A review

ŁJ Walczak-Nowicka, M Herbet - Nutrients, 2022 - mdpi.com
Currently, due to the large number of reports regarding the harmfulness of food additives,
more and more consumers follow the so-called “clean label” trend, ie, prefer and choose the …

Effect of sodium benzoate on cognitive function among patients with behavioral and psychological symptoms of dementia: secondary analysis of a randomized clinical …

CH Lin, PK Chen, SH Wang, HY Lane - JAMA network open, 2021 - jamanetwork.com
Importance Female gender is a major risk factor for dementia; however, gender has not yet
been adequately addressed by clinical trials. A recent study demonstrated that sodium …

Vitamin B12 ameliorate Tramadol-induced oxidative stress, endocrine imbalance, apoptosis and NO/iNOS/NF-κB expression in Sprague Dawley rats through …

SA Adelakun, VO Ukwenya, OW Akintunde - Tissue and Cell, 2022 - Elsevier
This study aimed at the effect of vitamin B 12 (VB 12) on tramadol (TRM) induced pituitary-
gonadal Axis toxicity. Thirty-two (32) adult male rats were randomized into four groups of …

Dose-dependent reproductive toxicity of sodium benzoate in male rats: Inflammation, oxidative stress and apoptosis

L El-Shennawy, MAE Kamel, AHY Khalaf… - Reproductive …, 2020 - Elsevier
The synthetic food preservative sodium benzoate (SB) is widely used in both food and
pharmaceutical industries. A growing body of evidence highlights the adverse effects of SB …

The modulatory role of vitamin C in boldenone undecylenate induced testicular oxidative damage and androgen receptor dysregulation in adult male rats

A Behairy, NI El-Sharkawy, TM Saber, MM Soliman… - Antioxidants, 2020 - mdpi.com
Background: This study explored the effect of vitamin C (Vit-C) administration on the
reproductive function of adult male Wistar rats injected with boldenone undecylenate (BOL) …

Zinc abates sodium benzoate-induced testicular dysfunction via upregulation of Nrf2/HO-1/Nf-κB signaling and androgen receptor gene

AJ Ajibare, AF Odetayo, OO Akintoye… - Journal of Trace …, 2024 - Elsevier
Abstract Background Sodium Benzoate (SB) is used in daily products such as drinks, juices,
sauces, oils, ketchup, toothpaste, mouthwashes, cosmetics, dentifrices, and pharmaceutical …

Protective role of glutamine against cadmium-induced testicular dysfunction in Wistar rats: involvement of G6PD activity

KS Olaniyi, OA Amusa, AA Oniyide, IO Ajadi… - Life sciences, 2020 - Elsevier
Background Endocrine disruptor such as cadmium has been widely reported to cause
testicular toxicity, which contributes to recent decline in male fertility worldwide. Glutamine …

Sodium benzoate induces neurobehavioral deficits and brain oxido‐inflammatory stress in male Wistar rats: Ameliorative role of ascorbic acid

FO Asejeje, BO Ajayi, MA Abiola… - … of Biochemical and …, 2022 - Wiley Online Library
Background Sodium benzoate (SB) is a widely used food preservative. However, excessive
intake of a high dose of SB poses a risk of neurotoxicity. Ascorbic acid (AA) is a naturally …

[HTML][HTML] Food additive (sodium benzoate)-induced damage on renal function and glomerular cells in rats; modulating effect of aqueous extract of Atriplex halimus L.

K Zeghib, DA Boutlelis - Iranian Journal of Pharmaceutical …, 2021 - ncbi.nlm.nih.gov
The aim of the current study was to investigate the preventive and curative effect of Atriplex
halimus L.(Ah) extract against the kidney damages induced by Sodium benzoate (SB) in …

Binding interaction of sodium benzoate food additive with bovine serum albumin: multi-spectroscopy and molecular docking studies

J Yu, JY Liu, WM Xiong, XY Zhang, Y Zheng - Bmc Chemistry, 2019 - Springer
Sodium benzoate (SB) is widely used as a preservative in food industry, and bovine serum
albumin (BSA) is a major carrier protein similar to human serum albumin (HSA), the study of …