Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment
Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer
The recent success of mRNA therapeutics against pathogenic infections has increased
interest in their use for other human diseases including cancer. However, the precise …
interest in their use for other human diseases including cancer. However, the precise …
Strategies to engineer various nanocarrier-based hybrid catalysts for enhanced chemodynamic cancer therapy
JN Hao, K Ge, G Chen, B Dai, Y Li - Chemical Society Reviews, 2023 - pubs.rsc.org
Chemodynamic therapy (CDT) is a newly developed cancer-therapeutic modality that kills
cancer cells by the highly toxic hydroxyl radical (˙ OH) generated from the in situ triggered …
cancer cells by the highly toxic hydroxyl radical (˙ OH) generated from the in situ triggered …
Overview and update on extracellular vesicles: considerations on exosomes and their application in modern medicine
MA Di Bella - Biology, 2022 - mdpi.com
Simple Summary Exosomes are a subpopulation of extracellular vesicles, nanosized
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …
Responsive exosome nano‐bioconjugates for synergistic cancer therapy
W Nie, G Wu, J Zhang, LL Huang, J Ding… - Angewandte Chemie …, 2020 - Wiley Online Library
Exosomes hold great potential in therapeutic development. However, native exosomes
usually induce insufficient effects in vivo and simply act as drug delivery vehicles. Herein, we …
usually induce insufficient effects in vivo and simply act as drug delivery vehicles. Herein, we …
Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors
S Dallavalle, V Dobričić, L Lazzarato, E Gazzano… - Drug Resistance …, 2020 - Elsevier
Multidrug resistance (MDR) is the dominant cause of the failure of cancer chemotherapy.
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …