The role of the 3'untranslated region in post-transcriptional regulation of protein expression in mammalian cells.
E Matoulkova, E Michalova, B Vojtesek, R Hrstka - RNA biology, 2012 - Taylor & Francis
The untranslated regions (UTRs) at the 3'end of mRNA transcripts contain important
sequences that influence the fate of mRNA and thus proteosynthesis. In this review, we …
sequences that influence the fate of mRNA and thus proteosynthesis. In this review, we …
VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level
T Arcondéguy, E Lacazette, S Millevoi… - Nucleic acids …, 2013 - academic.oup.com
Abstract Vascular Endothelial Growth Factor A (VEGF-A) is a potent secreted mitogen crucial
for physiological and pathological angiogenesis. Post-transcriptional regulation of VEGF-A …
for physiological and pathological angiogenesis. Post-transcriptional regulation of VEGF-A …
Intragenic antagonistic roles of protein and circRNA in tumorigenesis
Abstract circRNAs arise from back splicing events during mRNA processing, and when
deregulated can play an active role in cancer. Here we characterize a new circRNA …
deregulated can play an active role in cancer. Here we characterize a new circRNA …
Prognostic significance of copy-number alterations in multiple myeloma
H Avet-Loiseau, C Li, F Magrangeas… - Journal of Clinical …, 2009 - ascopubs.org
Purpose Chromosomal aberrations are a hallmark of multiple myeloma but their global
prognostic impact is largely unknown. Patients and Methods We performed a genome-wide …
prognostic impact is largely unknown. Patients and Methods We performed a genome-wide …
[HTML][HTML] TGFβ1 promotes gemcitabine resistance through regulating the LncRNA-LET/NF90/miR-145 signaling axis in bladder cancer
J Zhuang, L Shen, L Yang, X Huang, Q Lu, Y Cui… - Theranostics, 2017 - ncbi.nlm.nih.gov
High tumor recurrence is frequently observed in patients with urinary bladder cancers
(UBCs), with the need for biomarkers of prognosis and drug response. Chemoresistance …
(UBCs), with the need for biomarkers of prognosis and drug response. Chemoresistance …
[HTML][HTML] Long non-coding RNA DANCR stabilizes HIF-1α and promotes metastasis by interacting with NF90/NF45 complex in nasopharyngeal carcinoma
X Wen, XU Liu, YP Mao, XJ Yang, YQ Wang… - Theranostics, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) play an important role in the development and
progression of cancers. However, the clinical significances of lncRNAs and their functions …
progression of cancers. However, the clinical significances of lncRNAs and their functions …
Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6
TDP‐43 is an RNA/DNA‐binding protein implicated in transcriptional repression and mRNA
processing. Inclusions of TDP‐43 are hallmarks of frontotemporal dementia and …
processing. Inclusions of TDP‐43 are hallmarks of frontotemporal dementia and …
Emerging roles for RNA-binding proteins as effectors and regulators of cardiovascular disease
RG de Bruin, TJ Rabelink… - European heart …, 2017 - academic.oup.com
The cardiovascular system comprises multiple cell types that possess the capacity to
modulate their phenotype in response to acute or chronic injury. Transcriptional and post …
modulate their phenotype in response to acute or chronic injury. Transcriptional and post …
The Macrophage-Associated LncRNA MALR Facilitates ILF3 Liquid–Liquid Phase Separation to Promote HIF1α Signaling in Esophageal Cancer
J Liu, ZX Liu, JJ Li, ZL Zeng, JH Wang, XJ Luo… - Cancer Research, 2023 - AACR
Tumor-associated macrophages (TAM) are among the most abundant immune cells in the
tumor microenvironment and are important mediators of tumor development and …
tumor microenvironment and are important mediators of tumor development and …
Functional importance of Dicer protein in the adaptive cellular response to hypoxia
JJD Ho, JL Metcalf, MS Yan, PJ Turgeon… - Journal of Biological …, 2012 - ASBMB
The processes by which cells sense and respond to ambient oxygen concentration are
fundamental to cell survival and function, and they commonly target gene regulatory events …
fundamental to cell survival and function, and they commonly target gene regulatory events …