The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

Determinants of insecticide resistance evolution: comparative analysis among Heliothines

TK Walsh, DG Heckel, Y Wu, S Downes… - Annual Review of …, 2022 - annualreviews.org
It is increasingly clear that pest species vary widely in their propensities to develop
insecticide resistance. This review uses a comparative approach to analyze the key pest …

[HTML][HTML] Diversity and evolution of the P450 family in arthropods

W Dermauw, T Van Leeuwen, R Feyereisen - Insect biochemistry and …, 2020 - Elsevier
The P450 family (CYP genes) of arthropods encodes diverse enzymes involved in the
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …

Divergent amplifications of CYP9A cytochrome P450 genes provide two noctuid pests with differential protection against xenobiotics

Y Shi, Q Liu, W Lu, J Yuan, Y Yang… - Proceedings of the …, 2023 - National Acad Sciences
Here, we provide mechanistic support for the involvement of the CYP9A subfamily of
cytochrome P450 monooxygenases in the detoxification of host plant defense compounds …

Genome resequencing reveals rapid, repeated evolution in the Colorado potato beetle

B Pélissié, YH Chen, ZP Cohen… - Molecular Biology …, 2022 - academic.oup.com
Insecticide resistance and rapid pest evolution threatens food security and the development
of sustainable agricultural practices, yet the evolutionary mechanisms that allow pests to …

Genome-wide macroevolutionary signatures of key innovations in butterflies colonizing new host plants

R Allio, B Nabholz, S Wanke, G Chomicki… - Nature …, 2021 - nature.com
The mega-diversity of herbivorous insects is attributed to their co-evolutionary associations
with plants. Despite abundant studies on insect-plant interactions, we do not know whether …

Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics

D Amezian, R Nauen, G Le Goff - Insect Biochemistry and Molecular …, 2021 - Elsevier
Abstract The genus Spodoptera (Lepidoptera: Noctuidae) comprises some of the most
polyphagous and destructive agricultural pests worldwide. The success of many species of …

[HTML][HTML] A toxicogenomics approach reveals characteristics supporting the honey bee (Apis mellifera L.) safety profile of the butenolide insecticide flupyradifurone

J Haas, M Zaworra, J Glaubitz, G Hertlein… - Ecotoxicology and …, 2021 - Elsevier
Flupyradifurone, a novel butenolide insecticide, selectively targets insect nicotinic
acetylcholine receptors (nAChRs), comparable to structurally different insecticidal …

Chromosome-level genome assembly of Bactrocera dorsalis reveals its adaptation and invasion mechanisms

F Jiang, L Liang, J Wang, S Zhu - Communications Biology, 2022 - nature.com
Bactrocera dorsalis is an invasive polyphagous pest causing considerable ecological and
economic damage worldwide. We report a high-quality chromosome-level genome …

Chromosome‐level assembly of the melon thrips genome yields insights into evolution of a sap‐sucking lifestyle and pesticide resistance

SK Guo, LJ Cao, W Song, P Shi, YF Gao… - Molecular Ecology …, 2020 - Wiley Online Library
Thrips are tiny insects from the order Thysanoptera (Hexapoda: Condylognatha), including
many sap‐sucking pests that are causing increasing damage to crops worldwide. In contrast …