The therapeutic potential of dietary intervention: based on the mechanism of a tryptophan derivative-indole propionic acid on metabolic disorders

B Niu, T Pan, Y Xiao, H Wang, J Zhu… - Critical Reviews in …, 2023 - Taylor & Francis
Tryptophan (TRP) contributes to individual immune homeostasis and good condition via
three complex metabolism pathways (5-hydroxytryptamine (5-HT), kynurenine (KP), and gut …

Gut-liver Axis: Recent concepts in pathophysiology in alcohol-associated liver disease

FR Tonetti, A Eguileor, M Mrdjen, V Pathak… - Hepatology, 2024 - journals.lww.com
The growing recognition of the role of the gut microbiome's impact on alcohol-related
diseases, especially in alcohol-associated liver disease, emphasizes the need to …

Akkermansia muciniphila Ameliorates Alcoholic Liver Disease in Experimental Mice by Regulating Serum Metabolism and Improving Gut Dysbiosis

C Fang, J Cheng, W Jia, Y Xu - Metabolites, 2023 - mdpi.com
Alcoholic liver disease (ALD) represents a significant global health concern, yet the
available treatment options remain limited. Numerous studies have shown that gut …

17β-Estradiol protects female rats from bilateral oophorectomy-induced nonalcoholic fatty liver disease induced by improving linoleic acid metabolism alteration and …

Y Tian, Y Xie, X Hong, Z Guo, Q Yu - Heliyon, 2024 - cell.com
After surgical or natural menopause, women face a high risk of nonalcoholic fatty liver
disease (NAFLD), which can be diminished by hormone replacement therapy (HRT). The …

Minibioreactor arrays to model microbiome response to alcohol and tryptophan in the context of alcohol-associated liver disease

W Hu, S Naimi, N Trainel, V Liévin-Le Moal… - npj Biofilms and …, 2024 - nature.com
The intestinal microbiota (IM) plays a role in the severity of alcohol-associated liver disease.
Modifying severe alcohol-associated hepatitis (AH) dysbiosis improves liver injury through …

Nutritional deficiencies in alcohol use disorder/alcohol-associated liver disease

L Jophlin, TY Liu, CJ McClain - Current Opinion in …, 2024 - journals.lww.com
Nutritional deficiencies in alcohol use disorder/alcohol-ass... : Current Opinion in
Gastroenterology Nutritional deficiencies in alcohol use disorder/alcohol-associated liver …

Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway

M Tang, L Zhao, F Huang, T Wang, X Wu, S Chen… - Frontiers in …, 2024 - frontiersin.org
Introduction Alcoholic liver disease (ALD) is a pathological state of the liver caused by
longterm alcohol consumption. Recent studies have shown that the modulation of the gut …

Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway

JJ Jeong, YJ Jin, R Ganesan, HJ Park, BH Min… - Probiotics and …, 2024 - Springer
Diarrhea, a common gastrointestinal symptom in health problems, is highly associated with
gut dysbiosis. The purpose of this study is to demonstrate the effect of multistrain probiotics …

[HTML][HTML] A Butyrate-Yielding Dietary Supplement Prevents Acute Alcoholic Liver Injury by Modulating Nrf2-Mediated Hepatic Oxidative Stress and Gut Microbiota

Q Xu, M Guo, H Wang, H Liu, Y Wei, X Wang… - International Journal of …, 2024 - mdpi.com
Alcoholic liver disease (ALD) is a globally prevalent form of liver disease for which there is
no effective treatment. Recent studies have found that a significant decrease in butyrate was …

Machine Learning Metabolomics Profiling of Dietary Interventions from a Six-Week Randomised Trial

A Kouraki, A Nogal, W Nocun, P Louca, A Vijay… - Metabolites, 2024 - mdpi.com
Metabolomics can uncover physiological responses to prebiotic fibre and omega-3 fatty acid
supplements with known health benefits and identify response-specific metabolites. We …