Vitamin B12 (B12) is an essential cofactor of two important biochemical pathways, the
degradation of methylmalonic acid and the synthesis of methionine from homocysteine …

Diabetic neuropathy (DN), the most common chronic and progressive complication of
diabetes mellitus (DM), strongly affects patients' quality of life. DN could be present as …

Aims/hypothesis The individual risk of progression of diabetic peripheral neuropathy is
difficult to predict for each individual. Mutations in proteins that are responsible for the …

Background Nerve damage in diabetic neuropathy (DN) is assumed to begin in the distal
legs with a subsequent progression to hands and arms at later stages. In contrast, recent …

Clinical studies have suggested that changes in peripheral nerve microcirculation may
contribute to nerve damage in diabetic polyneuropathy (DN). High-sensitivity troponin T …

Objectives Clinical and histological studies have found evidence that nerve ischemia is a
major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D). The aim of this study …

Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood
complications of diabetes mellitus. In vivo imaging of dorsal root ganglia (DRG), a key …

Background Methods of data mining and analytics can be efficiently applied in medicine to
develop models that use patient-specific data to predict the development of diabetic …

Background and purpose Diabetic sensorimotor peripheral neuropathy is usually
considered to affect predominantly the lower limbs (LL‐N), whereas the impact of upper limb …

We aimed to investigate the characteristics and longitudinal course of sensory phenotypes
identified through quantitative sensory testing (QST) in the frame of diabetic sensorimotor …