Cerebral small vessel disease: from a focal to a global perspective

A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

Impact of diabetes on cognitive function and brain structure

A Moheet, S Mangia… - Annals of the New York …, 2015 - Wiley Online Library
Both type 1 and type 2 diabetes have been associated with reduced performance on
multiple domains of cognitive function and with structural abnormalities in the brain. With an …

Resting-state functional connectivity in normal brain aging

LK Ferreira, GF Busatto - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The world is aging and, as the elderly population increases, age-related cognitive decline
emerges as a major concern. Neuroimaging techniques, such as functional magnetic …

Cognitive function in patients with diabetes mellitus: guidance for daily care

PS Koekkoek, LJ Kappelle, E van den Berg… - The Lancet …, 2015 - thelancet.com
Diabetes mellitus is associated with an increase in the risk of dementia and the proportion of
patients who convert from mild cognitive impairment (MCI) to dementia. In addition to MCI …

Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders

RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

Resting-state functional MR imaging: a new window to the brain

F Barkhof, S Haller, SARB Rombouts - Radiology, 2014 - pubs.rsna.org
Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel
paradigm that examines spontaneous brain function by using blood oxygen level …

Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI?

GJ Biessels, YD Reijmer - Diabetes, 2014 - Am Diabetes Assoc
Diabetes is associated with cognitive dysfunction and an increased risk of dementia. This
article addresses findings with brain MRI that may underlie cognitive dysfunction in diabetes …

[HTML][HTML] Diabetic retinopathy is a neurodegenerative disorder

SK Lynch, MD Abràmoff - Vision research, 2017 - Elsevier
Since 1875, controversy has ensued over whether ocular diabetic complications are
primarily vasculopathic or neuropathic in nature. Here, we discuss the historical context by …

Intranasal insulin enhanced resting-state functional connectivity of hippocampal regions in type 2 diabetes

H Zhang, Y Hao, B Manor, P Novak, W Milberg… - Diabetes, 2015 - Am Diabetes Assoc
Type 2 diabetes mellitus (T2DM) alters brain function and manifests as brain atrophy.
Intranasal insulin has emerged as a promising intervention for treatment of cognitive …

[HTML][HTML] Diabetes mellitus in the young and the old: Effects on cognitive functioning across the life span

E van Duinkerken, CM Ryan - Neurobiology of disease, 2020 - Elsevier
Mild to moderate cognitive decrements are a well-known phenomenon associated with
diabetes mellitus. In this review, we provide an overview of the cognitive consequences of …