Cardiac troponins are sensitive and specific markers of myocardial injury. The troponin
concentration can be thought of as a quantitative measure of the degree of injury sustained …

There is an overwhelming weight of evidence that certifies cardiac troponin (cTn) as the
preferred, defacto, translational, safety biomarker for myocardial injury in cardiotoxicity. As …

Rats have long been recognized as a valuable biomedical research model, notably in the
investigation of aging, toxicology, addiction, and common human diseases such as diabetes …

Background Doxorubicin (DOX) is commonly used in the treatment of many types of cancers
but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin …

Aims Doxorubicin, an antibiotic belonging to anthracycline family, has been used for
treatment of malignancies. Cardiotoxicity is the main adverse effect of doxorubicin. Apigenin …

10+ Years of Updates Since First EditionNewcomers to the animal clinical chemistry and
toxicology fields quickly find that the same rules of human medicine do not always apply …

Cardiomyopathy is a progressive disease of the myocardium leading to impaired
contractility. Genotoxic cancer therapies are known to be potent drivers of cardiomyopathy …

Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …

Preventive treatment with cannabinoid agonists has been reported to reduce the infarct size
in a mouse model of myocardial ischemia/reperfusion. Here we investigated the possible …

The purpose of this study was to determine the serological and molecular prevalence of
Bartonella spp. infection in a sick dog population from Brazil. At the São Paulo State …