RNA-based liquid biopsy in head and neck cancer

J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Cancer-associated fibroblasts: Mediators of head and neck tumor microenvironment remodeling

M Raudenska, J Balvan, K Hanelova… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cancer-associated fibroblasts (CAFs) are involved in critical aspects of head and neck
squamous cell carcinoma (HNSCC) pathogenesis, such as the formation of a tumor …

Glutamine and serum starvation alters the ATP production, oxidative stress, and abundance of mitochondrial RNAs in extracellular vesicles produced by cancer cells

M Bugajova, M Raudenska, K Hanelova, J Navratil… - Scientific Reports, 2024 - nature.com
Induction of autophagy represents an effective survival strategy for nutrient-deprived or
stressed cancer cells. Autophagy contributes to the modulation of communication within the …

Metabolic pathway-based subtypes associate glycan biosynthesis and treatment response in head and neck cancer

B Dankó, J Hess, K Unger, D Samaga, C Walz… - NPJ Precision …, 2024 - nature.com
Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous
malignancy that remains a significant challenge in clinical management due to frequent …

Long-term zinc treatment alters the mechanical properties and metabolism of prostate cancer cells

J Navratil, M Kratochvilova, M Raudenska… - Cancer Cell …, 2024 - Springer
The failure of intracellular zinc accumulation is a key process in prostate carcinogenesis.
Although prostate cancer cells can accumulate zinc after long-term exposure, chronic zinc …

The interplay between microbiome and host factors in pathogenesis and therapy of head and neck cancer

M Raudenská, M Bugajová, D Kalfeřt, J Plzák… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Heterogeneous cancers that lack strong driver mutations with high penetrance, such as
head and neck squamous cell carcinoma (HNSCC), present unique challenges to …

Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck …

M Rademaekers, EO Johansson, E Johansson… - Cancer Cell …, 2024 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs) are the major cellular
component of the tumor microenvironment and are known to affect tumor growth and …

Integrating single-cell and bulk RNA sequencing to predict prognosis and immunotherapy response in prostate cancer

XY Wen, RY Wang, B Yu, Y Yang, J Yang… - Scientific Reports, 2023 - nature.com
Prostate cancer (PCa) stands as a prominent contributor to morbidity and mortality among
males on a global scale. Cancer-associated fibroblasts (CAFs) are considered to be closely …